Abstract: Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereoselectively one of a pair of chiral amines in which the amino group is bound to a non-terminal, chirally substituted, carbon atom.
Type:
Grant
Filed:
December 7, 2005
Date of Patent:
February 6, 2007
Assignee:
Cambrex North Brunswick, Inc.
Inventors:
Sachin Pannuri, Sanjay Venkatesh Kamat, Abraham Rogelio Martin Garcia