Abstract: A device mouthpiece is provided wherein the mouthpiece comprises a cylindrical tube and a filter element, wherein the filter element comprises a frame and a filter medium secured to the frame; the frame defines an annular channel which receives therein an end portion of the cylindrical tube; the end portion of the cylindrical tube forms a friction fit within the annular channel; and wherein the filter element is secured to the cylindrical tube via the friction fit.

Abstract: A device mouthpiece is provided wherein the mouthpiece comprises a cylindrical tube and a filter element, wherein the filter element comprises a frame and a filter medium secured to the frame; the frame defines an annular channel which receives therein an end portion of the cylindrical tube; the end portion of the cylindrical tube forms a friction fit within the annular channel; and wherein the filter element is secured to the cylindrical tube via the friction fit.

Abstract: A process for the production of a device having a surface microstructure of wells or channels. In the process one or more steps of screen-printing the microstructure as a curable material onto a plastic substrate, and curing the material. Such a device is also obtained by applying onto a substrate a material that is polymerizable or depolymerizable by irradiation, applying a negative or positive resist photoresist respectively, irradiating the structure and removing the unpolymerized or depolymerized material.

Abstract: A device, for use in the electrochemical analysis of an analyte in a small volume liquid sample, having a non-conducting substrate (1); a conductive layer, deposited on the substrate, in two parts (2a, 2b), defining a non-conducting gap (8) therebetween; an analyte-specific reagent (5) coated on the conductive layer, on one side of the gap; a reference electrode (3) on the conductive layer, on the other side of the gap; a spacer layer (4) deposited over the conductive layer; a monofilament mesh (6) coated with a surfactant or chaotropic agent, the mesh being laid over the reagent, the reference electrode and the spacer layer; and a second non-conductive layer (7) adhered to the mesh layer, but not coextensive therewith, thereby providing a sample application area (9) on the mesh.

Abstract: An electrode comprises a non-conductive substrate and a conductive layer comprising, in a bonded matrix, graphite particles coated with a noble metal, and carbon particles, wherein the graphite particles are up to 20 &mgr;m is size and have a surface area of 1-50 m2/g. This electrode is capable of measuring low levels of analyte, e.g. glucose in sweat when convined with a layer containing glucose oxidase.