Abstract: A method of making a transistor having first and second electrodes, a semiconductive layer, and a dielectric layer; said semiconductive layer comprising a semiconductive polymer and said dielectric layer comprising an insulating polymer; characterised in that said method comprises the steps of: (i) depositing on the first electrode a layer of a solution containing material for forming the semiconductive layer and material for forming the dielectric layer; and (ii) optionally curing the layer deposited in step (i); wherein, in step (i), the solvent drying time, the temperature of the first electrode and the weight ratio, of (material for forming the dielectric layer): (material for forming the semiconductive layer) in the solution are selected so that the material for forming the semiconductive layer and the material for forming the dielectric layer phase separate by self-organisation to form an interface between the material for forming the semiconductive layer and the material for forming the dielectric l

Abstract: A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence.

Abstract: The present invention relates to a method of producing an ultrahydrophobic surface, the method comprising providing a mixture comprising low surface energy material and a sacrificial material, forming a layer from the mixture wherein the layer contains particles of the sacrificial material, treating the layer so as to destroy the particles of sacrificial material and generate a laterally continuous matrix of solid low surface energy material containing an array of depressions.

Abstract: A support structure (1) is provided comprising a plurality of curved surfaces A, B hingedly interconnected along their edges such as to provide effective deployment in two separate stages. Preferably, the structure has only two curved surfaces hingedly interconnected at a single non-planar hinge line. In FIG. 1(a), the two sheets A, B are coplanar in that they lie in the same horizontal plane, permitting the structure to be in a flat, first stage deployment position. In Figure (b), the structure is fully deployed in a second stage deployment position by bringing sheet A out of plane through some angle in relation to the position of sheet B, resulting in both sheets becoming curved. The structure has utility in various space-based as well as terrestrial reflective and absorbing applications, and bears definite advantage in terms of weight saving, high stiffness and well-defined surface precision.

Abstract: A method for forming an organic or partly organic switching device, comprising: depositing layers of conducting, semiconducting and/or insulating layers by solution processing and direct printing; defining microgrooves in the multilayer structure by solid state embossing; and forming a switching device inside the microgroove.

Abstract: This invention relates to methods of testing, diagnosing, monitoring, prognostically stratifying and classifying disease, disorders and other medical conditions and physiological states through the detection and analysis of soluble CD antigens in a body fluid sample.

Abstract: A patterning method comprises selectively depositing droplets of a first material solvent solution onto a layer of a second material. The solvent is chosen to dissolve both materials, which are selected so as to exhibit phase separation upon the removal of the solution to provide domains of the first material embedded in and extending through the second material. By selection of appropriate materials the patterning method may be used, for example, to fabricate light emitting devices, optical color filters, or vertical interconnects in electronic devices.

Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.

Abstract: A dendron (2) comprising a focal point (4) and a plurality of fluorinated end groups (9) is disclosed, including one having a thiol, a silane, a carboxylic acid, a phosphonate or another moiety at the focal point suitable for chemisorption to a substrate (3). A self-assembled monolayer comprising a plurality of dendrons bonded to a substrate and a device comprising the self-assembled monolayer are also disclosed.

Abstract: A method of identifying features within a dataset such as an image comprises applying a multiscale transform such as a dual tree Complex Wavelet Transform to generate a plurality of scale-related transform levels each having a plurality of transform coefficients defining magnitude and phase; determining the phase difference between a first coefficient on one level, and a second coefficient on the same or a different level; and identifying the feature in dependence on the phase difference. Each quadrant of the phase difference, when plotted as an angle, is indicative of a different type of feature. The invention is equally applicable to the identification of two-dimensional features such as images, as well as to the identification of features within one-dimensional data streams such as audio.

Abstract: The invention relates to improved terahertz radiation sources and associated methods. A terahertz radiation source is described, comprising: an emitter (202) comprising a semiconductor material (12); a pair of electrodes (204a,b) adjacent a face of said semiconductor, said pair of electrodes defining a gap between said electrodes; a pulsed light source input for illuminating said semiconductor to excite photo-carriers in said semiconductor to generate terahertz radiation; and a radiation collector (212) to collect said terahertz radiation; and wherein said radiation collector is disposed on the same side of said semiconductor as said electrodes. A related method of providing terahertz radiation is also described.

Abstract: To provide a catalyst for synthesis reaction which can achieve good yield in the Sonogashira reaction and also can be recovered after the reaction, and a method for synthesizing a compound in which the catalyst for synthesis reaction is used, a perovskite-type composite oxide containing palladium is used as the catalyst for synthesis reaction in the Sonogashira reaction represented by the following reaction scheme (1): R1—X+HC?CR2?R1C?CR2??(1)

Abstract: This invention relates to methods and means for assessing cognitive dysfunction, in particular impulsivity associated cognitive dysfunction, which may for example include Attention Deficit Hyperactivity Disorder (ADHD), substance abuse, and non-toxic addictive/compulsive behaviour. A method may comprise displaying a population of elements to the individual and allowing the sequential selection of elements within the population by the individual. The selection of an element reveals to the individual a characteristic of the selected element which is one of a number of possible characteristics of elements in said population. The sequential selection ends when the individual chooses which of the possible characteristics is possessed by the most elements in the population. The number of elements selected by the individual in making this choice is then correlated to the likelihood that the individual has impulsivity associated cognitive dysfunction.

Abstract: The invention provides apparatus for producing an extrudate product including a plurality of capillary channel. The apparatus comprises an extruder having an inlet, a die including an orifice having a predetermined outer shape and a plurality of needles each having a body including an internal conduit for fluid flow. Each needle further comprises an outlet from the internal conduit at an outlet end. The outlet end of each needle is arranged in a predetermined pattern substantially within the orifice of the die and the conduit of each needle is fluidly connected to a fluid source. In use extrudable material is fed into the extruder through the inlet. The extruder forces the extrudable material around the bodies of the needles towards the die and through the orifice in the die to produce an extrudate having substantially the predetermined outer shape.

Abstract: A catalyst for synthesis reaction that can allow the cross coupling reaction at an improved yield, and yet can be collected after used for the reaction and recycled, and a synthesizing method for a compound using the same catalyst for synthesis reaction.

Abstract: A method for forming an organic or partly organic switching device. The method comprises depositing layers of conducing, semiconducting and/or insulating layers by solution processing and direct printing. Then, high-resolution patterns of electroactive polymers are formed by self-aligned formation of a surface energy barrier around a first pattern that repels the solution of a second material.

Abstract: There is provided a human myeloma cell tine for use in a method for producing a human monoclonal antibody.

Abstract: A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in hydrophobicity (?Hydr) between the reference polypeptide and a modified polypeptide, calculating the difference in ?-sheet propensity (??Gcoil-?+??G?-coil) between the reference polypeptide and modified polypeptide, calculating the difference in charge (? Charge) between the reference polypeptide and modified polypeptide, and calculating: [x*?Hydr]+[y*(??Gcoil-?+??G?-coil)]?[z*? Charge], wherein x, y and z are scaling factors.

Abstract: A continuous method is provided for recycling a metal/organic laminate comprising metal, such as aluminium, laminated with an organic material, the method comprising: providing a reactor (1) comprising a first chamber (2) having a first rotary stirrer (4) and a second chamber (3) having a second rotary stirrer (5), each chamber (2, 3) containing a bed of particulate microwave absorbing material; introducing laminate and additional particulate microwave absorbing material into the first chamber (2) via an inlet (6); under a reducing or inert atmosphere stirring the mixture of particulate microwave absorbing material and laminate in the first chamber (2) using the first rotary stirrer (3) and applying microwave energy in the first chamber (2) to heat the particulate microwave absorbing material to a temperature sufficient to pyrolyse organic material in the laminate; transferring a portion of the mixture in the first chamber (2) to the second chamber (3); stirring the mixture in the second chamber (3) using the

Abstract: A process for production of an agglomerate comprises the steps of: passing a flow of one or more gaseous reactants into a reactor; reacting the one or more gaseous reactants within a reaction zone of the reactor to form product particles; agglomerating the product particles into an agglomerate; and applying a force to the agglomerate to displace it continuously away from the reaction zone.