Patents Assigned to Campina-Melkunie B.V.
  • Patent number: 7977066
    Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides. The aqueous peptide mixture is preferably obtained by enzymatic cleavage at acidic pH of a protein source. Further, peptides having a Trp content of 8-15 w/w % and the use thereof as a food additive and as an active ingredient in a medicament are described.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: July 12, 2011
    Assignee: Campina Melkunie B.V.
    Inventors: Leon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans
  • Patent number: 6753022
    Abstract: The invention relates to a method for preparing a dairy product, in which a medium comprising milk or a milk product is treated under aerobic conditions with a lactose-negative, food-technologically acceptable microorganism, and is then kept under anaerobic conditions for some time. Furthermore, the invention relates to a dairy product obtainable by this method.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: June 22, 2004
    Assignee: Campina Melkunie B.V.
    Inventors: Reinier Johannes C. Vermin, Henry-Eric Spinnler
  • Patent number: 6620778
    Abstract: Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into peptides; b) digesting the peptides obtained in step a) by an exopeptidase, the action of which is at least attenuated at the position of a cysteine in the peptide, therewith forming digested peptides having a terminal cysteine; c) purifying the digested peptides, and the use of the preparation as active component in a medicament, especially for the treatment of conditions mediated by oxidative damage and for the elevation of cellular glutathion levels in the human or animal body.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: September 16, 2003
    Assignee: Campina Melkunie B.V.
    Inventors: Leon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
  • Publication number: 20030114364
    Abstract: The present invention relates to a method of reducing dental plaque and calculus deposition. The invention further relates to a method of treating or preventing periodonitis and other diseases of the teeth and tissues of the oral cavity. The invention further relates to compositions suitable for use in such methods.
    Type: Application
    Filed: October 4, 2002
    Publication date: June 19, 2003
    Applicant: CAMPINA MELKUNIE B.V.
    Inventors: Steven D. Braun, Ram Nimmagudda
  • Patent number: 6514941
    Abstract: The present invention relates, in general, to a casein hydrolysate, and, in particular, to a method of preparing a casein hydrolysate enriched in antihypertensive peptides.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: February 4, 2003
    Assignee: Campina Melkunie B.V.
    Inventors: J. Kelly Tolton, II, Ram Nimmagudda, Steven D. Braun, Michael Primmer, Frans van der Veerdonk
  • Patent number: 6482396
    Abstract: The present invention relates to a method of reducing dental plaque and calculus deposition. The invention further relates to a method of treating or preventing periodonitis and other diseases of the teeth and tissues of the oral cavity. The invention further relates to compositions suitable for use in such methods.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: November 19, 2002
    Assignee: Campina Melkunie B.V.
    Inventors: Steven D. Braun, Ram Nimmagudda
  • Patent number: 6447811
    Abstract: A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic microorganisms such as fungi and bacteria. Preferably the formulation also contains an oil.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: September 10, 2002
    Assignees: Koppert B.V., Campina-Melkunie B.V.
    Inventors: Willem Jacobus Ravensberg, Richard Karel Van der Pas, Klaas Daniel Kussendrager, Johannes Antonius Maria Maas
  • Publication number: 20020090670
    Abstract: Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of:
    Type: Application
    Filed: October 23, 2001
    Publication date: July 11, 2002
    Applicant: Campina Melkunie B.V.
    Inventors: Leon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
  • Patent number: 6010698
    Abstract: The invention relates to a process for recovering one or more growth factors from milk or a milk derivative, comprising adsorbing at least one growth factor from the milk or the milk derivative to a cation exchanger, followed by fractionated elution of the cation exchanger, whereby at least one fraction is obtained which is enriched in growth factors, followed by the further treatment of this fraction at a pH of at least 3.5 and not more than 4.5.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: January 4, 2000
    Assignee: Campina Melkunie B. V.
    Inventors: Klaas Daniel Kussendrager, Marinus Gerardus Cornelis Kivits, Hubert Karel Lemmen, Theodorus Johannes Antonia Maria van Kessel
  • Patent number: 5650190
    Abstract: The invention relates to a heat-stable oil-in-water emulsion comprising hydrolyzed protein as well as hydrolyzed lecithin having a degree of hydrolysis above 40%, to a powdery product obtained by drying an emulsion according to the invention, as well as to a dry, mixed product comprising hydrolyzed protein and hydrolyzed lecithin. The invention further relates to the use of hydrolyzed lecithin as stabilizer in oil-in-water emulsions comprising hydrolyzed protein.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: July 22, 1997
    Assignee: Campina Melkunie, B.V.
    Inventors: Friso Pieter Martinus Buikstra, Albertus Jacobus Martinus Maria van der Kruis, Petrus Henricus Nicolaas van der Heijden
  • Patent number: 5534555
    Abstract: A tableting excipient for making tablets by direct tableting in the form of a homogeneous mass consisting of a dried solution of lactose having a high .beta.-lactose content, to which solution 1-15 wt. % of a sugar alcohol, calculated on the solids of the solution to be dried, has been added prior to drying.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: July 9, 1996
    Assignee: Campina Melkunie B.V.
    Inventors: Michael M. Meggelaars, Henricus A. van den Biggelaar, Klaas D. Kussendrager
  • Patent number: 5478591
    Abstract: An alcoholic beverage based on dairy constituents, such as milk protein and optionally milk fat-containing products, one or more fruit juices, such as fruit juices chosen from juice from berries, cherries, citrus, mint, strawberry, raspberry, plums, peaches, tropical fruits and combinations thereof, cocoa constituents, one or more stabilizers and optionally one or more thickeners is described.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: December 26, 1995
    Assignee: Campina Melkunie B.V.
    Inventors: Johannes A. M. Bevers, Johannes A. Bindels, Martinus M. G. M. van den Hoven
  • Patent number: 5420249
    Abstract: This invention relates to a process for the recovery of .alpha.-lactalbumin and/or .beta.-lactoglobulin enriched whey protein concentrate from a whey protein product. The process comprises the following steps:a) incubating a solution comprising whey protein product with a calcium-binding ionic exchange resin in its acid form to initiate the instabilization of .alpha.-lactalbumin,b) adjusting the pH of the treated protein product solution to a value between 4.3 and 4.8, after separation of the resin,c) incubating the protein product solution at a temperature between 10 and 50.degree. C. to promote the flocculation of .alpha.-lactalbumin,d) fractionating the proteins in the protein product solution at pH 4.3-4.8, providing an .alpha.-lactalbumin enriched fraction and a .beta.-lactoglobulin enriched fraction,e) raising the pH of the .alpha.-lactalbumin enriched fraction sufficiently to solubilize the .alpha.-lactalbumin fraction, andf) optionally raising the pH of the .beta.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: May 30, 1995
    Assignee: Campina Melkunie B.V.
    Inventors: Jacobus N. de Wit, Henricus Bronts