Patents Assigned to Campina-Melkunie B.V.
-
Patent number: 7977066Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides. The aqueous peptide mixture is preferably obtained by enzymatic cleavage at acidic pH of a protein source. Further, peptides having a Trp content of 8-15 w/w % and the use thereof as a food additive and as an active ingredient in a medicament are described.Type: GrantFiled: October 23, 2008Date of Patent: July 12, 2011Assignee: Campina Melkunie B.V.Inventors: Leon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans
-
Patent number: 6753022Abstract: The invention relates to a method for preparing a dairy product, in which a medium comprising milk or a milk product is treated under aerobic conditions with a lactose-negative, food-technologically acceptable microorganism, and is then kept under anaerobic conditions for some time. Furthermore, the invention relates to a dairy product obtainable by this method.Type: GrantFiled: May 23, 2001Date of Patent: June 22, 2004Assignee: Campina Melkunie B.V.Inventors: Reinier Johannes C. Vermin, Henry-Eric Spinnler
-
Patent number: 6620778Abstract: Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into peptides; b) digesting the peptides obtained in step a) by an exopeptidase, the action of which is at least attenuated at the position of a cysteine in the peptide, therewith forming digested peptides having a terminal cysteine; c) purifying the digested peptides, and the use of the preparation as active component in a medicament, especially for the treatment of conditions mediated by oxidative damage and for the elevation of cellular glutathion levels in the human or animal body.Type: GrantFiled: October 23, 2001Date of Patent: September 16, 2003Assignee: Campina Melkunie B.V.Inventors: Leon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
-
Publication number: 20030114364Abstract: The present invention relates to a method of reducing dental plaque and calculus deposition. The invention further relates to a method of treating or preventing periodonitis and other diseases of the teeth and tissues of the oral cavity. The invention further relates to compositions suitable for use in such methods.Type: ApplicationFiled: October 4, 2002Publication date: June 19, 2003Applicant: CAMPINA MELKUNIE B.V.Inventors: Steven D. Braun, Ram Nimmagudda
-
Patent number: 6514941Abstract: The present invention relates, in general, to a casein hydrolysate, and, in particular, to a method of preparing a casein hydrolysate enriched in antihypertensive peptides.Type: GrantFiled: December 17, 1999Date of Patent: February 4, 2003Assignee: Campina Melkunie B.V.Inventors: J. Kelly Tolton, II, Ram Nimmagudda, Steven D. Braun, Michael Primmer, Frans van der Veerdonk
-
Patent number: 6482396Abstract: The present invention relates to a method of reducing dental plaque and calculus deposition. The invention further relates to a method of treating or preventing periodonitis and other diseases of the teeth and tissues of the oral cavity. The invention further relates to compositions suitable for use in such methods.Type: GrantFiled: May 15, 2001Date of Patent: November 19, 2002Assignee: Campina Melkunie B.V.Inventors: Steven D. Braun, Ram Nimmagudda
-
Patent number: 6447811Abstract: A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic microorganisms such as fungi and bacteria. Preferably the formulation also contains an oil.Type: GrantFiled: June 30, 2000Date of Patent: September 10, 2002Assignees: Koppert B.V., Campina-Melkunie B.V.Inventors: Willem Jacobus Ravensberg, Richard Karel Van der Pas, Klaas Daniel Kussendrager, Johannes Antonius Maria Maas
-
Publication number: 20020090670Abstract: Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of:Type: ApplicationFiled: October 23, 2001Publication date: July 11, 2002Applicant: Campina Melkunie B.V.Inventors: Leon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
-
Patent number: 6010698Abstract: The invention relates to a process for recovering one or more growth factors from milk or a milk derivative, comprising adsorbing at least one growth factor from the milk or the milk derivative to a cation exchanger, followed by fractionated elution of the cation exchanger, whereby at least one fraction is obtained which is enriched in growth factors, followed by the further treatment of this fraction at a pH of at least 3.5 and not more than 4.5.Type: GrantFiled: March 24, 1998Date of Patent: January 4, 2000Assignee: Campina Melkunie B. V.Inventors: Klaas Daniel Kussendrager, Marinus Gerardus Cornelis Kivits, Hubert Karel Lemmen, Theodorus Johannes Antonia Maria van Kessel
-
Patent number: 5650190Abstract: The invention relates to a heat-stable oil-in-water emulsion comprising hydrolyzed protein as well as hydrolyzed lecithin having a degree of hydrolysis above 40%, to a powdery product obtained by drying an emulsion according to the invention, as well as to a dry, mixed product comprising hydrolyzed protein and hydrolyzed lecithin. The invention further relates to the use of hydrolyzed lecithin as stabilizer in oil-in-water emulsions comprising hydrolyzed protein.Type: GrantFiled: May 4, 1995Date of Patent: July 22, 1997Assignee: Campina Melkunie, B.V.Inventors: Friso Pieter Martinus Buikstra, Albertus Jacobus Martinus Maria van der Kruis, Petrus Henricus Nicolaas van der Heijden
-
Patent number: 5534555Abstract: A tableting excipient for making tablets by direct tableting in the form of a homogeneous mass consisting of a dried solution of lactose having a high .beta.-lactose content, to which solution 1-15 wt. % of a sugar alcohol, calculated on the solids of the solution to be dried, has been added prior to drying.Type: GrantFiled: June 20, 1994Date of Patent: July 9, 1996Assignee: Campina Melkunie B.V.Inventors: Michael M. Meggelaars, Henricus A. van den Biggelaar, Klaas D. Kussendrager
-
Patent number: 5478591Abstract: An alcoholic beverage based on dairy constituents, such as milk protein and optionally milk fat-containing products, one or more fruit juices, such as fruit juices chosen from juice from berries, cherries, citrus, mint, strawberry, raspberry, plums, peaches, tropical fruits and combinations thereof, cocoa constituents, one or more stabilizers and optionally one or more thickeners is described.Type: GrantFiled: May 12, 1995Date of Patent: December 26, 1995Assignee: Campina Melkunie B.V.Inventors: Johannes A. M. Bevers, Johannes A. Bindels, Martinus M. G. M. van den Hoven
-
Process for the recovery of .alpha.-lactalbumin and .beta.-lactoglobulin from a whey protein product
Patent number: 5420249Abstract: This invention relates to a process for the recovery of .alpha.-lactalbumin and/or .beta.-lactoglobulin enriched whey protein concentrate from a whey protein product. The process comprises the following steps:a) incubating a solution comprising whey protein product with a calcium-binding ionic exchange resin in its acid form to initiate the instabilization of .alpha.-lactalbumin,b) adjusting the pH of the treated protein product solution to a value between 4.3 and 4.8, after separation of the resin,c) incubating the protein product solution at a temperature between 10 and 50.degree. C. to promote the flocculation of .alpha.-lactalbumin,d) fractionating the proteins in the protein product solution at pH 4.3-4.8, providing an .alpha.-lactalbumin enriched fraction and a .beta.-lactoglobulin enriched fraction,e) raising the pH of the .alpha.-lactalbumin enriched fraction sufficiently to solubilize the .alpha.-lactalbumin fraction, andf) optionally raising the pH of the .beta.Type: GrantFiled: December 20, 1993Date of Patent: May 30, 1995Assignee: Campina Melkunie B.V.Inventors: Jacobus N. de Wit, Henricus Bronts