Abstract: The present invention relates to a method for preventing HLA alloimmune response to platelet transfusion. The method comprises the step of presensitizing platelets with at least one monoclonal HLA antibody. The platelets if administered to a patient prevent an HLA alloimmune response from said patient.
Type:
Grant
Filed:
November 10, 2000
Date of Patent:
June 15, 2004
Assignee:
Canadian Blood Services
Inventors:
Alan H. Lazarus, John Freedman, Andrew R. Crow
Abstract: The present invention relates to a novel method for producing human natural interferon-&agr; using ex vivo expanded cord blood hematopoietic cells infected with sendaivirus, on a large scale.