Patents Assigned to Cancer Research Malaysia
  • CANCER VACCINE
    Publication number: 20220233666
    Abstract: The present invention relates to nucleic acid vaccines which encode at least a MAGED4B protein, for use in the treatment of cancer in particular. Synergistic combinations with other anti-cancer agents are described, particularly immune checkpoint inhibitors. The cancer vaccine may further comprise an immunologically active fragment to enhance the immune response, and an additional cancer antigen, such as FJX1. Particular combination therapies of interest include immunotherapies, radiotherapy, targeted therapies and chemotherapies.
    Type: Application
    Filed: October 19, 2020
    Publication date: July 28, 2022
    Applicants: University of Southampton, Cancer Research Malaysia
    Inventors: Natalia SAVELYEVA, Gareth THOMAS, Christian OTTENSMEIER, Chuan WANG, Sok Ching CHEONG, Kue Peng LIM
  • Immunogenic peptide composition
    Patent number: 11260118
    Abstract: The present invention relates to a peptide composition capable of binding with major histocompatibility complex class I molecules to induce an anti-cancer immune response in a subject. Particularly, the peptide composition comprises at least a Four-jointed Box 1 peptide and a Melanoma Antigen family D4b peptide. The present invention further relates to the use of a peptide composition and a peptide vaccine for inducing the anti-cancer immune response in the subject.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: March 1, 2022
    Assignee: Cancer Research Malaysia
    Inventors: San Jiun Chai, Sammuel Chee Yong Fong, Chai Phei Gan, Sathibalan Ponniah, Vyomesh Patel, Sok Ching Cheong, Kue Peng Lim