Abstract: The present invention relates generally to an apparatus and methods for predicting disease and, more specifically, to an apparatus and methods for detecting and diagnosing cancer. One embodiment of the present invention may include generating mass spectra data from a sample taken from a subject and comparing the sample to a prediction model to assess whether or not the subject has a specific disease. Another embodiment of the present invention may include generating a first set of mass spectra data from samples taken from a population known to have a disease and generating a second set of mass spectra data from samples taken from a population known not to have the disease. The two sets of mass spectra data may then be compared to identify markers in the spectra data indicating the presence of the disease.

Abstract: The present invention relates to an apparatus and methods of testing and predicting a patient's response to a treatment for a disease. In one embodiment, the present invention relates to an apparatus and methods of testing and predicting a patient's chemosensitivity before the patient begins chemotherapy. The invention may include the steps of generating mass spectra data from samples taken from a population that responds to a treatment of a disease, generating mass spectra data from samples taken from a population that does not respond to the same treatment of the disease, and comparing the two sets of data. The presence or non-presence of a peak in the compared data may be markers indicating the likelihood of response to the treatment of the disease.

Abstract: Filters and methods for enhancing the identification of peaks is disclosed. In particular, the invention encompasses methods using hole array filters for the purpose of purifying biological fluids to be used in generating mass spectra data.

Abstract: Filters and methods for enhancing the identification of peaks is disclosed. In particular, the invention encompasses methods using hole array filters for the purpose of purifying biological fluids to be used in generating mass spectra data.