Abstract: The invention provides certain compositions and methods for dental care, which alone or in combination with other dental technologies can help to achieve better outcomes in terms of the enhancement of oral hygiene as regards to preservation of the healthy oral and/or dental flora, minimization or a reduction of the proportion of harmful bacteria, and further facilitate the enhancement of a more healthy appearance of teeth and gums. The oral formulation for improving oral and/or dental hygiene, and/or for enhancing the healthy appearance of teeth and gums, comprises Dead Sea salt and at least one synthetic, semi-synthetic or natural cannabinoid, a precursor, a derivative, or any combination thereof, or an extract of a cannabis plant.

Abstract: The current invention discloses a system for detecting an intraoral disease and determining a personalized treatment scheme; the system comprising: a. a reservoir configured for accommodating a sample of a biologic material collected in an oral cavity of a patient; b. a first detector for detecting a first substance originating from bacteria; c. a second detector for detecting a second substance originating from at least one of an immune and an inflammatory system of the patient; d. a control unit configured for operatively receiving signals from the first and second detectors and analyzing the signals; and e. display and communication means configured for presenting results of signal analysis; wherein the control unit is configured for determining said treatment scheme comprising relevant antimicrobial compositions and a dosing frequency thereof. Additionally, the present invention recommends customized cannabis-based oral care products.