Abstract: One or more devices, systems, methods, and storage mediums for performing self-diagnosis using one or more imaging modalities are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Devices, systems, methods, and storage mediums may include or involve a method, such as, but not limited to, for determining status or health (such as optical health) of a rotary joint of an apparatus/system and/or of the apparatus/system. A device, system, method, or storage medium may perform self-diagnosis or diagnosis to minimize, reduce, and/or avoid optical failures, rotary joint failures, or apparatus/system failures and to have a robust method(s) of determining the health of the rotary joint and/or the apparatus or system.

Abstract: A catheter, comprising: a drive cable having cylindrical opening extending from a proximal end to a distal end along a longitudinal axis thereof; an imaging probe having an optical fiber arranged inside the drive cable and a distal optics assembly fixedly attached to the drive cable at the distal end thereof; a first radiopaque marker arranged at a distal end of the drive cable at a position distal and parallel to the distal optics assembly; and a second radiopaque marker arranged at a predetermined distance from the distal end of the drive cable at a position proximal to the distal optics assembly. The second radiopaque marker is arranged concentric or coaxially to the longitudinal axis in a space between the longitudinal axis and an outer surface of the drive cable.

Abstract: An articulated medical device having a hollow core, capable of large degrees of maneuverability through small spaces of a patient to reach a target with minimal invasiveness, and once the medical device has reached the target, allowing a medical tool to be guided through the hollow chamber for facilitating medical procedures, including endoscopes, cameras, and catheters, at the target.

Abstract: Devices, systems, and methods obtain first imaging data and first timestamps that correspond to the first imaging data; obtain second imaging data and second timestamps that correspond to the second imaging data; demodulate the first imaging data to acquire a first timing signal; demodulate the second imaging data to acquire a second timing signal; and calculate a delay value based on the first timing signal, the second timing signal, the first timestamps, and the second timestamps.

Abstract: A multimodality system includes first and second modalities, an optical probe, a detector, and a sheath with a known fluorescence phantom, wherein the phantom would be used for calibration of the catheter providing accurate NIRAF values to the user using the sheath phantom to calibrate an optical probe's measured NIRAF signal to the known fluorescence of the phantom.

Abstract: A method for intravascular image processing carries out steps of acquiring intravascular data of a portion of a lumen, determining a region of interest based on characteristics of the acquired data, determining an angle (orientation) for displaying an initial longitudinal view of the portion of the lumen based on the determined region of interest, and displaying the initial longitudinal view based on the determined angle and displaying a tomographic view of the portion of the lumen.

Abstract: A method for visualization guidance of device-to-image registration includes acquiring image data of a patient, generating a 3D model of the anatomy of the patient based on the image data, performing initial registration between image space and device space, advancing a device into a structure, tracking trajectory of the device in relation to the model, determining divergence between the device trajectory and the model, and effecting correction to the model or the device trajectory to minimize the divergence.

Abstract: A control system controls an endoscope probe in manual mode or robot mode. The system comprises a handle attached to the probe; a portable display controller connectable to the handle; a robotic controller in communication with the handle and/or the portable display controller; and a support platform to which the probe and the portable device controller are attachable according to control mode. In manual mode, the handle is detached from the platform and connected to the portable display controller such that the probe is manually navigated to a first position inside a lumen. In robot mode, the handle is attached to the platform such that the robotic controller cooperates with the handle to robotically navigate the probe to a second position inside the lumen. The portable display controller includes a control section for manipulating the probe and a display section for displaying images of the lumen acquired in both modes.

Abstract: One or more devices, systems, methods, and storage mediums for imaging and more particularly to minimally invasive medical devices, such as, but not limited to, spectrally encoded endoscopy (SEE), endoscopy, and/or other catheter-related apparatuses and systems, methods, and storage mediums for use with same, are provided herein. One or more devices, systems, methods and storage mediums may be for characterizing, examining and/or diagnosing, and/or measuring viscosity of, a sample or object in application(s) using an apparatus or system that includes, in one or more embodiments, an in-situ optics observation window or lens cleaning apparatus or system that provides a technique(s) for cleaning the medical device optic(s) without removing the medical device during a surgical procedure.

Abstract: One or more devices, systems, methods, and storage mediums using artificial intelligence application(s) using an apparatus or system that uses and/or controls one or more imaging modalities, such as, but not limited to, angiography, Optical Coherence Tomography (OCT), Multi-modality OCT, near-infrared fluorescence (NIRAF), OCT-NIRAF, etc. are provided herein.

Abstract: A robot-assisted endoscope system and control methods thereof allow a user to perform intraluminal interventional procedures using a steerable sheath. A processor generates a ghost image based on a non-real-time insertion trajectory of the sheath, and a real-time image based on a real-time insertion trajectory for inserting an interventional tool through the sheath towards the target site. A display screen outputs navigation guidance data for informing a user how to manipulate the distal section of the sheath towards the target site such that the real-time image overlaps or coincides with at least part the ghost image and the real-time insertion trajectory becomes aligned with the non-real-time insertion trajectory.

Abstract: A method and system for calibrating fluorescence data in a multimodality image acquired from a vessel imaged by an imaging catheter. A fluorescence signal acquired by a first modality is calibrated by applying a first calibration factor based on a lumen distance and/or radiation angle from the catheter to the vessel wall. If a parameter of the calibrated fluorescence signal is different from a predetermined condition, a user is prompted to manually select a lumen boundary and/or a region of interest (ROI) on the image of the vessel. An optical attenuation property of the selected boundary and/or ROI is calculated based on backscattered radiation collected by a second modality, and the fluorescence signal is further calibrated by applying a second calibration factor based on the optical attenuation property.

Abstract: An optical coherence tomography (OCT) system comprises: an imaging catheter; a calibration phantom removably arranged at least partially surrounding the distal end of the catheter; and a processor configured to control the catheter to acquire OCT images. The phantom has known dimensions and specific optical properties which provide non-changing calibration fiducials that span the imaging range of the system. The phantom is imaged by the catheter upon first connection to the system. The processor calculates a thickness of the phantom in the OCT image, and preforms z-offset calibration by setting the position of a phantom surface in the OCT image to a known nominal value. The known nominal value is related to one or more of the known thickness of the phantom or a diameter of the catheter sheath or a nominal angle of the light beam or the imaging range of the system.

Abstract: An optical connection includes a first connector, a second connector, a first holder connected to the first connector, where the first connector is secured by the first holder by tight fitting or bonding, and a second holder connected to the second connector, where the second connector is secured by the second holder by tight fitting or bonding. An adapter can be configured to connect with the first connector and the second connector, and a third holder can be connected to the adapter and interconnected between the first holder and the second holder.

Abstract: Embodiments disclosed herein provide systems, methods and/or computer-readable media for automatically detecting and removing fluorescence artifacts from catheter-based multimodality OCT-NIRAF images. In one embodiment, a process of determining an automatic threshold value (automatic thresholding) is implemented by sorting characteristic parameter values of the NIRAF signal and finding a maximum perpendicular distance between a curve of the sorted values and a straight line from the highest to the lowest sorted value, combined with the use of unsupervised machine learning classification techniques to detect the frame's NIRAF values that correspond to signal artifacts. Once the signal artifacts are detected, the system can filter out the signal artifacts, correct the frames that had artifacts, and produce a more accurate multimodality image.

Abstract: One or more devices, systems, methods and storage mediums for optical imaging medical devices, and methods and storage mediums for use with same, for viewing, controlling, updating, and emphasizing one or more imaging modalities and/or for constructing or reconstructing 2D and/or 3D structure(s) are provided herein. One or more embodiments provide at least one intuitive Graphical User Interface (GUI), method, device, apparatus, system, or storage medium to comprehend information, including, but not limited to, molecular structure of a vessel, and to provide an ability to manipulate the vessel information and/or to construct or reconstruct 2D and/or 3D structure(s) of the vessel to improve or maximize accuracy in one or more images. In addition to controlling one or more imaging modalities, the GUI may operate for one or more applications, including, but not limited to, expansion/underexpansion (e.g., for a stent) and/or apposition/malapposition (e.g., for a stent), co-registration, and imaging.

Abstract: One or more devices, systems, methods, and storage mediums for performing image synchronization using one or more imaging modalities are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Devices, systems, methods, and storage mediums may include or involve a method, such as, but not limited to, for performing image synchronization.

Abstract: An apparatus, method, and system for a cable jacket having a resealable closure, where the closure is adapted to protect the inner elements of the jacket without exposure to outside contaminants, even when the jacket is manipulated by bending and/or twisting.

Abstract: A runner for supplying resin to a cavity includes a sprue that is supplied resin from a nozzle of an injection molding machine, a first path formed in the runner, where the resin flows in the first path from the nozzle when the nozzle connects to the sprue, a first pin that moves to a first position to increase the size of the first path before the resin is supplied to the first path and moves to a second position to decrease the size of the first path before the nozzle separates from the sprue.

Abstract: An injection molding system including an injection molding apparatus that performs injection molding, and a conveyor apparatus configured to insert a mold through an opening of the injection molding apparatus, wherein the improvement to the injection molding system includes the injection molding apparatus further comprising a first door configured to restrict access via a first opening when a first door is closed and a second door configured to restrict access via a second opening when a second door is closed, and a controller configured to start injection molding with the mold in a case where the first door is partially opened and the second door is closed.