Patents Assigned to Caphalon Australia Pty. Ltd.
  • VARIANT DOMAIN ANTIBODIES
    Publication number: 20110319597
    Abstract: The present invention relates to domain antibodies which have modified framework regions such that the potency or level of binding of the domain antibody is improved. In particular the present invention relates to domain antibodies which bind TNFa in which changes have been made to framework sequences and to constructs including these domain antibodies.
    Type: Application
    Filed: August 13, 2009
    Publication date: December 29, 2011
    Applicant: Caphalon Australia Pty. Ltd.
    Inventors: Raina Jui Yu Simpson, Zehra Elgundi, Anthony Gerard Doyle, Philip Anthony Jennings, Robert Daniel Gay, Adam William Clarke