Abstract: The present invention relates to methods for detecting a genetic deletion at the SHOX locus of a horse, where the presence of such a genetic deletion indicates that the horse is a carrier of disease-causing mutation that can lead to skeletal atavism. The invention further provides nucleic acid primers and probes for use in methods for detecting the presence or absence of disease-causing genetic deletion at the SHOX locus of a horse.
Type:
Grant
Filed:
June 11, 2018
Date of Patent:
March 29, 2022
Assignees:
CAPILET GENETICS AB, UNIVERSITY OF WASHINGTON
Inventors:
Sofia Mikko, Leif Andersson, Gabriella Lindgren, Carl-Johan Rubin, Bhanu Chowdhary, Terje Raudsepp, Evan E. Eichler, John Huddleston, Maika Malig
Abstract: The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed.
Type:
Grant
Filed:
August 21, 2017
Date of Patent:
August 13, 2019
Assignee:
CAPILET GENETICS AB
Inventors:
Lisa S. Andersson, Leif Andersson, Gabriella Lindgren
Abstract: The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed.
Type:
Application
Filed:
July 9, 2015
Publication date:
December 31, 2015
Applicant:
CAPILET GENETICS AB
Inventors:
Lisa S. Andersson, Leif Andersson, Gabriella Lindgren
Abstract: The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed.
Type:
Application
Filed:
August 25, 2014
Publication date:
February 12, 2015
Applicant:
CAPILET GENETICS AB
Inventors:
Lisa S. Andersson, Leif Andersson, Gabriella Lindgren
Abstract: The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed.
Type:
Application
Filed:
May 4, 2012
Publication date:
February 27, 2014
Applicant:
CAPILET GENETICS AB
Inventors:
Lisa S. Andersson, Leif Andersson, Gabriella Lindgren