Abstract: Provided is a composition for prevention or treatment of an allergic disease, the composition including an inotodiol compound and a chaga mushroom (Inonotus obliquus) extract including an inotodiol compound as an active ingredient. More particularly, it was found that when an inotodiol compound or a chaga mushroom extract containing an inotodiol compound as one of the active ingredients is administered to a mouse model in which a food allergy was induced, symptoms induced by the allergy were alleviated and cured. Thus, the inotodiol compound or the chaga mushroom extract containing an inotodiol compound as an active ingredient is expected to be useful as a composition for prevention or treatment of an allergic disease.

Abstract: Provided is a composition including a fraction of the Syzygium formosum extract as an active ingredient, which inhibits the expression of inflammatory cytokines to prevent, ameliorate, or treat inflammation disease, and when the composition is included in cosmetics, the prepared cosmetics may have high stability.

Abstract: The present disclosure relates to inotodiol as a liver X receptor agonist and use thereof for the treatment of a liver X receptor-mediated disease. Inotodiol according to an aspect, or a prodrug thereof has LXR?-specific agonist activity, and thus not only has remarkable safety compared to other LXR agonists, but can also be effectively used in the treatment of LXR-related diseases, such as a neurodegenerative brain disease, an autoimmune disease, NASH, and NAFLD.

Abstract: The present disclosure relates to an ester derivative prodrug of inotodiol and use thereof. The prodrug not only has increased solubility with respect to an inorganic solvent and an organic solvent, but also has improved stability, and thus can be used in the treatment of various inflammatory diseases, including inflammatory diseases or allergic diseases.

Abstract: Provided are a method of manufacturing a functional polysaccharide, the method including: preparing a cell containing a polysaccharide; crushing the cell to extract polysaccharide to the outside of the cell to obtain an extract; and purifying the extract by removing at least one of crude protein, crude fat, and crude powder from the extract, and a cosmetic composition for skin moisturizing or skin elasticity improvement, the cosmetic composition including the functional polysaccharide as an active ingredient.

Abstract: Provided is a composition for prevention or treatment of an allergic disease, the composition including an inotodiol compound and a chaga mushroom (Inonotus obliquus) extract including an inotodiol compound as an active ingredient. More particularly, it was found that when an inotodiol compound or a chaga mushroom extract containing an inotodiol compound as one of the active ingredients is administered to a mouse model in which a food allergy was induced, symptoms induced by the allergy were alleviated and cured. Thus, the inotodiol compound or the chaga mushroom extract containing an inotodiol compound as an active ingredient is expected to be useful as a composition for prevention or treatment of an allergic disease.