Abstract: Systems and methods related to the computerized synthesis of simulated health data are provided. A computing device can receive a respective data model constructed from protected health information (PHI) hosted by a respective health data provider. The computing device can create a state transition machine from the received data model, where a state of the state transition machine represents a health related event of a synthetic life. The computing device can generate a synthetic health data set for each synthetic person in a synthetic population by calculating one or more health related events for each time step in the synthetic life. The computing device can calculate a similarity score by comparing the generated synthetic health data set to an actual health data set. The computing device can adjust the received data model based on the score falling below a threshold similarity, thereby creating an adjusted data model.