Abstract: This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, PCSK9, or a pharmaceutically acceptable salt, solvate, prodrug or polymorph thereof, and to compositions and formulations comprising such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I): wherein A, D and Q are described herein.
Type:
Grant
Filed:
June 30, 2021
Date of Patent:
February 13, 2024
Assignee:
CARDIO THERAPEUTICS PTY LTD
Inventors:
Herbert Treutlein, Jun Zeng, Ian Dixon, Ian James, James T. Palmer
Abstract: This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, PCSK9, or a pharmaceutically acceptable salt, solvate, prodrug or polymorph thereof, and to compositions and formulations comprising such compounds, and methods of using and making such compounds. Compounds include comprising of Formula (I): (I) wherein A, D and Q are described herein.
Type:
Grant
Filed:
March 16, 2018
Date of Patent:
August 17, 2021
Assignee:
CARDIO THERAPEUTICS PTY LTD
Inventors:
Herbert Treutlein, Jun Zeng, Ian Dixon, Ian James, James T. Palmer