Abstract: The present invention relates to wound closure devices, devices and systems for delivery, kits and methods therefor. The wound closure devices can achieve wound closure in lieu of compression and can be configured to be quickly deployable by an introducer or from outside the body.

Abstract: A vascular closure system includes a swellable or bioabsorbable sealing element and a plunger advancement tool. The sealing element and plunger advancement tool is configured to be inserted into the inside of a tubular medical device (such as a vascular introducer sheath, catheter, cannula, trocar, electrode wire, etc.) with the sealing element being advanced distally past the end of the tubular medical device to a desired area within the body (near or at least partially within an arteriotomy, for example) by the plunger. Once in contact with blood (or other fluid) the sealing element may swell, sealing the puncture site. The system may include one of several different features designed to assist the physician to position the sealing element in the desired location. Additional versions of the system described herein can be used for cardiovascular applications where hemostasis (temporary or permanent) is desired.

Abstract: The present invention relates to tissue closure devices, devices and systems for delivery, kits and methods therefor. The tissue closure devices can achieve tissue closure in lieu of compression and can be configured to be quickly deployable by an introducer or from outside the body.

Abstract: A deflectable component for a motorized vehicle can include a deflectable part formed at least partially from a superelastic and or shape memory material, wherein at least a portion of the deflectable component is moved to a deflected position upon application of a threshold force when moving at or above a predetermined speed, and returning to an undeflected position when moving below the predetermined speed. The deflectable component may comprise a connection link fabricated at least partially from a superelastic and/or shape memory material to tailor the flex point characteristics of a connected surface to a desired response. The deflectable component may improve the performance of motorized vehicles by improving the aerodynamic and fuel efficiency, as well as other beneficial effects.

Abstract: Methods and devices for a coupler adapted and configured for use with a device insertable within a mammalian body are disclosed. The devices comprise, for example, an elongate member having a lumen therethrough; and a flange extending from the elongate member at a first end further comprising a tissue engaging surface; an opening along a length of the elongate member having a width less than a diameter of the insertable device and adapted and configured to engage the insertable device within the lumen of the elongate member.