Patents Assigned to CARDIOVAX, LLC
  • Publication number: 20180318387
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: June 15, 2018
    Publication date: November 8, 2018
    Applicant: CardioVax, LLC
    Inventors: Christopher John Farina, Bertrand C. Liang, Stacey Ruiz
  • Publication number: 20180289780
    Abstract: Described herein are compositions comprising osteopontin (OPN) or an antigenic fragment thereof and a protein carrier and uses of the compositions to treat cardiovascular diseases.
    Type: Application
    Filed: April 6, 2018
    Publication date: October 11, 2018
    Applicant: CardioVax, LLC
    Inventors: Jan Nilsson, Claes Pontus Duner
  • Publication number: 20170340702
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: May 31, 2017
    Publication date: November 30, 2017
    Applicant: CardioVax, LLC
    Inventors: Mark Carvlin, Jan Nilsson, Stacey Ruiz
  • Publication number: 20170100432
    Abstract: The present disclosure relates to antigen specific tolerogenic antigen presenting cells presenting antigenic portions of an autoantigen and to related compositions, methods and systems.
    Type: Application
    Filed: November 15, 2016
    Publication date: April 13, 2017
    Applicant: CardioVax, LLC
    Inventors: Goran Hansson, Andreas Hermansson
  • Patent number: 9221876
    Abstract: The invention provides compositions comprising immunogenic fragments of ApoB-100 for eliciting an immune response in a subject or vaccinating a subject, so as to treat, prevent, 5 inhibit and/or reduce symptoms of kidney diseases in the subject. The compositions include immunogenic fragments of ApoB-100, CD8+ T cells activated with immunogenic fragments of ApoB-100 or a combination thereof.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: December 29, 2015
    Assignee: CardioVax, LLC
    Inventors: Kuang-Yuh Chyu, Prediman K. Shah, Paul Dimayuga
  • Patent number: 9205139
    Abstract: Immunomodulatory agents, T cell, compositions, methods and systems for treating and/or preventing an aneurysm and/or a condition associated thereto in an individual.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: December 8, 2015
    Assignee: CardioVax, LLC
    Inventors: Prediman K. Shah, Kuang-Yuh Chyu, Tomoyuki Honjo
  • Patent number: 8647628
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: February 11, 2014
    Assignee: Cardiovax, LLC
    Inventors: Jan Nilsson, Prediman K. Shah
  • Patent number: 8642726
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of the antibodies.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: February 4, 2014
    Assignee: CardioVax, LLC
    Inventors: Jan Nilsson, Prediman K. Shah
  • Patent number: 8642043
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of the antibodies.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: February 4, 2014
    Assignee: CardioVax, LLC
    Inventors: Jan Nilsson, Prediman K. Shah
  • Patent number: 8609605
    Abstract: Immunostimulatory methods and systems for treating or preventing atherosclerosis and/or a condition associated thereto in an individual.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: December 17, 2013
    Assignee: CardioVax, LLC
    Inventor: Goran Hansson
  • Patent number: 8506964
    Abstract: A fusion protein comprising an antigenic fragment of apoB-100 and a suitable carrier and related compositions methods and systems.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: August 13, 2013
    Assignee: CardioVax, LLC
    Inventors: Jan Nilsson, Goran K. Hansson, Jan Holmgren
  • Patent number: 8436139
    Abstract: The present invention relates to a fragment of apolipoprotein B, for immunization for prophylactic or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, in particular myocardial infarction or stroke, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing ischemic cardiovascular diseases including stroke, using said peptide in an assay, pharmaceutical compositions comprising the peptide. The invention further encompasses a particular peptide sequence aggravating disease, which sequence then can be used for diagnostic assays.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: May 7, 2013
    Assignee: CardioVax, LLC
    Inventor: Göran K. Hansson
  • Patent number: 8435532
    Abstract: The present invention relates to the use of fibronectin, tenascin, collagens type I, III, VI and/or VIII modified by aldehyde or by glycosylation in ELISA for detection of antibodies in plasma and serum to diagnose atherosclerosis as well as the use of induction of tolerance and active as well as passive immunization against glycosylated or aldehydemodified fibronectin, tenascin, collagen type I, III, VI and/or VIII for prevention and treatment of atherosclerosis.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: May 7, 2013
    Assignee: CardioVax, LLC
    Inventor: Jan Nilsson
  • Publication number: 20120301491
    Abstract: The present invention relates to the use of fibronectin, tenascin, collagens type I, III, VI and/or VIII modified by aldehyde or by glycosylation in ELISA for detection of antibodies in plasma and serum to diagnose atherosclerosis as well as the use of induction of tolerance and active as well as passive immunization against glycosylated or aldehydemodified fibronectin, tenascin, collagen type I, III, VI and/or VIII for prevention and treatment of atherosclerosis.
    Type: Application
    Filed: August 7, 2012
    Publication date: November 29, 2012
    Applicant: CARDIOVAX, LLC
    Inventor: Jan Nilsson