Abstract: This document is related to a method for determining the cardio-generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
Type:
Application
Filed:
May 20, 2010
Publication date:
April 26, 2012
Applicants:
CARDIO3 BIOSCIENCES SA, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors:
Andre Terzic, Atta Behfar, Roland Gordon-Beresford, Vinciane Gaussin, Christian Homsy