Abstract: A surgical device is provided for forming a channel through or into tissue utilizing both mechanical energy and laser energy. The device includes a needle for forming the first part of the channel. The needle has an open bore. Mounted within the bore is an optical fiber for emitting laser energy to form the balance of the channel.

Abstract: Devices and methods for effective administration of therapeutic drugs or gene therapy to the myocardium is achieved by creating a trap or pocket within the myocardium for confining the injected therapeutic. The pocket can be created using mechanical and light energy, or other means.

Abstract: A surgical device is provided for forming a channel through or into tissue utilizing radio-frequency electrical energy. The device includes a cannula having an open bore. Mounted within the bore is an insulated mono-polar electrical lead, the distal end of which is not insulated, for forming the channel by mechanically advancing through the tissue and emitting radio-frequency energy. Alternatively, the device can have bipolar electrical leads.

Abstract: A surgical device is provided for forming a channel through or partially through vascular tissue, including vascular tissue, utilizing both mechanical and laser energy, and, if desired, depositing a therapeutic agent therein. The device includes an optical fiber for transmission of laser energy, a housing, and a hollow guide attached to the housing through which the optical fiber extends. A needle is attached to the distal end of the optical fiber in fluid communication with a catheter surrounding the optical fiber. Additionally, an actuator is included operably connected to the optical fiber for selectively extending the needle and/or fiber from the hollow guide. Finally, a laser control device is contemplated operably connected to the optical fiber, transmitting laser energy from the distal end of the fiber after the needle has penetrated a layer of selected distance into the tissue.

Abstract: Devices and methods for effective administration of therapeutic drugs or gene therapy to the myocardium is achieved by creating a trap or pocket within the myocardium for confining the injected therapeutic. The pocket can be created using mechanical and light energy, or other means.

Abstract: A surgical device is provided for forming a channel through or into tissue utilizing both mechanical energy and laser energy. The device includes a needle for forming the first part of the channel. The needle has an open bore. Mounted within the bore is an optical fiber for emitting laser energy to form the balance of the channel.

Abstract: A surgical device is provided for forming a channel through or into tissue utilizing both mechanical energy and laser energy. The device includes a needle for forming the first part of the channel. The needle has an open bore. Mounted within the bore is an optical fiber for emitting laser energy to form the balance of the channel.

Abstract: A stethoscope, operable in an acoustic or electronically augmented mode, is disclosed. In one electronically augmented mode of operation, the stethoscope simultaneously provides the listener with combined unmodified, familiar audible sounds and sounds which have been electronically augmented to bring them within the human auditory range. Additionally, a timing sound may be provided along with the unmodified, familiar audible sounds and electronically augmented sounds to assist the listener in determining when sounds occur in the heart cycle. The timing sound may be enabled in the acoustic mode of stethoscope operation so that the listener can place familiar audible sounds within the heart cycle.

Abstract: A recording device using a portable recorder, such as a small, battery powered tape recorder, carried on the person and provided with electrodes for attachment to the body of the user, the electrodes being operable to sense cardiac activity and to provide the input signals to a program module coupled with the recorder to cause the latter to be turned on and off at predetermined times so that it operates at predetermined periods for the purpose of recording samples of the user's cardiac activity sensed by the electrodes. The program module operates to amplify the input signals from the electrodes and to cause these signals to modulate a carrier wave signal suitable for recording by the tape or other recorder. The program module also is operable to demodulate the carrier wave signal when it is played back from the recorder to reproduce an accurate reproduction of the input signals from the electrodes.