Abstract: A method and device for sealing an opening in an anatomical structure within a living body involves the positioning of the tissue adjacent to the opening within a gap formed by a central part of a flexible tube between proximal and distal parts thereof. A movable surface coupled to the central part is also provided so that, in a first configuration, the movable surface is substantially continuous with outer surfaces of the proximal and distal parts and, in a second configuration, the movable surface projects away from the outer surfaces of the proximal and distal parts. A first needle coupled to a suture loop is drawn from a needle retention channel formed within the distal part through the tissue received in the gap and into a needle receiving channel formed within the proximal part. After the device has been rotated to a second position, the procedure is repeated and a second needle attached to the suture loop is drawn through the tissue in the same manner.

Abstract: A device for locating and sealing a small incision or puncture in a blood vessel includes a housing with a plurality of openings formed therethrough. A plunger is slidably mounted in the housing and has a plurality of apertures formed therethrough. The apertures in the plunger are aligned with the openings in the housing. A tube extends through each of the aligned apertures and openings and accommodates a piercing stylet that extends through the tubes. A suture guide extends from one end of the housing for releasably retaining a suture therein.

Abstract: A device for sealing a puncture in a tissue within a living body, comprises a flexible tube including an opening, wherein the flexible tube extends from a proximal end which, when the device is in an operative position, is located outside the living body, to a distal end which, in the operative position, is located within the living body on a distal side of the puncture in combination with an inner member received within the flexible tube so that the inner member may move proximally and distally with respect to the flexible tube. A first end of a flexible anchor member is coupled to the inner member so that, when the inner member is moved with respect to the outer member, a second end of the anchor member extends through the opening outside the flexible tube.