Patents Assigned to Cardiolynx AG
  • EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE
    Publication number: 20180008558
    Abstract: The present invention relates to extended release compositions of an amino-C2-C6-alkyl nitrate and of pharmaceutically acceptable salt thereof, in particular 2-aminoethyl nitrate, and to fixed dose combinations with further pharmaceutically active drug substances. 2-Aminoethyl nitrate does not provoke nitrate tolerance, but has a very short half life in physiological systems.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 11, 2018
    Applicant: CARDIOLYNX AG
    Inventors: Dirk SARTOR, Pierre VANKAN, Hubert STUCKLER, Armin SCHERHAG
  • EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE
    Publication number: 20170100350
    Abstract: The present invention relates to extended release compositions of an amino-C2-C6-alkyl nitrate and of pharmaceutically acceptable salt thereof, in particular 2-aminoethyl nitrate, and to fixed dose combinations with further pharmaceutically active drug substances. 2-Aminoethyl nitrate does not provoke nitrate tolerance, but has a very short half life in physiological systems.
    Type: Application
    Filed: December 23, 2016
    Publication date: April 13, 2017
    Applicant: CARDIOLYNX AG
    Inventors: Dirk SARTOR, Pierre VANKAN, Hubert STUCKLER, Armin SCHERHAG
  • Valsartan derivatives carrying nitrogen oxide donors for the treatment of vascular and metabolic diseases
    Patent number: 8729115
    Abstract: Nitrate esters and diazeniumdiolate derivatives of valsartanamide are described. They have valuable properties in the treatment of vascular and metabolic diseases.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: May 20, 2014
    Assignee: Cardiolynx AG
    Inventors: Dirk Sartor, Armin Scherhag
  • Nitrate and diazeniumdiolate derivatives of pioglitazone
    Patent number: 8703800
    Abstract: Nitrate ester and diazeniumdiolate derivatives of pioglitazone are described. They have valuable properties in the treatment of vascular and metabolic diseases, for example type 2 diabetes.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: April 22, 2014
    Assignee: Cardiolynx AG
    Inventors: Dirk Sartor, Armin Scherhag
  • Nitrate derivatives of cilostazol for the treatment of vascular and metabolic diseases
    Patent number: 8426597
    Abstract: Nitrate derivatives of cilostazol are described. They have superior properties and clinical advantages compared to cilostazol in the treatment of vascular and metabolic diseases.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: April 23, 2013
    Assignee: Cardiolynx AG
    Inventors: Dirk Sartor, Armin Scherhag