Abstract: Use of urodilatin for preparing a medicament for the treatment of cardiovascular, renal, pulmonary and neuronal syndromes while avoiding a rebound, wherein said medicament for the delivery of urodilatin is suitable in a first quantity for a first period of at least 48 hours, followed by delivery over a second period of at least 12 hours with successive reduction of said first quantity continuously or gradually to 0 ng/kg/min.
Abstract: The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute decompensated heart failure. Preferably, a composition comprising an effective amount of urodilatin is intravenously administered to the patient continuously through a time period of at least 24 hours and up to 120 hours, preferably at least 48 hours.
Type:
Grant
Filed:
April 26, 2010
Date of Patent:
April 29, 2014
Assignee:
Cardiopep Pharma GmbH
Inventors:
Veselin Mitrovic, Hartmut Luss, Wolf-Georg Forssmann, Markus Meyer, Klaus Dohler
Abstract: The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute decompensated heart failure. Preferably, a composition comprising an effective amount of urodilatin is intravenously administered to the patient continuously through a time period of at least 24 hours and up to 120 hours, preferably at least 48 hours.
Type:
Application
Filed:
April 26, 2010
Publication date:
October 20, 2011
Applicant:
CARDIOPEP PHARMA GMBH
Inventors:
Veselin Mitrovic, Hartmut L?ss, Wolf-Georg Forssmann, Markus Meyer, Klaus D?hler
Abstract: The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute decompensated heart failure. Preferably, a composition comprising an effective amount of urodilatin is intravenously administered to the patient continuously through a time period of at least 24 hours and up to 120 hours, preferably at least 48 hours.
Type:
Grant
Filed:
April 7, 2006
Date of Patent:
June 8, 2010
Assignee:
CardioPep Pharma GmbH
Inventors:
Veselin Mitrovic, Hartmut Lüss, Wolf-Georg Forssmann, Markus Meyer, Klaus Döhler
Abstract: The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute decompensated heart failure. Preferably, a composition comprising an effective amount of urodilatin is intravenously administered to the patient continuously through a time period of at least 24 hours and up to 120 hours, preferably at least 48 hours.
Type:
Application
Filed:
April 7, 2006
Publication date:
November 23, 2006
Applicant:
Cardiopep Pharma GmbH
Inventors:
Veselin Mitrovic, Hartmut Luss, Wolf-Georg Forssmann, Markus Meyer, Klaus Dohler