Patents Assigned to Cardiovention, Inc.
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Patent number: 7541000Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: GrantFiled: September 26, 2005Date of Patent: June 2, 2009Assignee: Cardiovention, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Ben F. Brian, III, Fred I. Linker, James M. Culp, Jean-Pierre Dueri, Thomas A. Afzal
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Patent number: 7291124Abstract: A tubing set for use with a blood handling system is described that decreases the priming volume and surface area of the blood handling circuit, lowering the risk of hemodilution, platelet activation, and hemolysis. The tubing set also reduces the number of manual connections required, and uses quick-disconnect couplings to facilitate connections between the various lines, and between the lines and the arterial and venous cannulae.Type: GrantFiled: May 6, 2005Date of Patent: November 6, 2007Assignee: Cardiovention, Inc.Inventors: Thomas A. Rawles, A. Kenneth Litzie, David M. Fallen, Steven K. Stringer
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Publication number: 20060177343Abstract: Apparatus for oxygenating and pumping blood includes a housing defining a blood flow path including, in series, a gas collection plenum, a pump space and a blood oxygenation element. A pump disposed in the pump space is configured to draw blood from the gas collection plenum and propel blood from the pump space through a heat exchanger and the blood oxygenation element. The heat exchanger includes a heat exchange plate and a coolant space.Type: ApplicationFiled: April 3, 2006Publication date: August 10, 2006Applicant: Cardiovention, Inc.Inventors: Ben Brian, John Buckley, Jean-Pierre Dueri, Mehrdad Farhangnia, Steven Stringer
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Patent number: 7022099Abstract: Apparatus for processing blood in an extracorporeal circuit with automatic flow control is provided in which error conditions are sensed and system operation is modulated responsive to the error conditions. The apparatus includes an extracorporeal blood processing system, at least one sensor that senses the presence or absence of gas or monitors venous pressure, and a controller operably coupled to the blood processing system to selectively reduce pump speed or to reconfigure flow paths within the blood processing system responsive to the sensor output.Type: GrantFiled: March 17, 2003Date of Patent: April 4, 2006Assignee: Cardiovention, Inc.Inventors: A. Kenneth Litzie, Steven K. Stringer, Mehrdad Farhangnia, Muslim Tyebjee, Thomas A. Afzal, Ben F. Brian, III
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Patent number: 7022284Abstract: Apparatus for oxygenating and pumping blood includes a housing defining a blood flow path including, in series, a gas collection plenum, a pump space and a blood oxygenation element. A pump disposed in the pump space is configured to draw blood from the gas collection plenum and propel blood from the pump space through a heat exchanger and the blood oxygenation element. The heat exchanger includes a heat exchange plate and a coolant space.Type: GrantFiled: May 9, 2003Date of Patent: April 4, 2006Assignee: Cardiovention, Inc.Inventors: Ben F. Brian, John Thomas Buckley, Jean-Pierre Dueri, Mehrdad Farhangnia, Steven K. Stringer
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Publication number: 20060029515Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: ApplicationFiled: September 26, 2005Publication date: February 9, 2006Applicant: Cardiovention, Inc.Inventors: Steven Stringer, Kevin Hultquist, Mehrdad Farhangnia, Ben Brian, Fred Linker, James Culp, Jean-Pierre Dueri, Thomas Afzal
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Publication number: 20060009728Abstract: Apparatus for processing blood in an extracorporeal circuit with automatic flow control is provided in which error conditions are sensed and system operation is modulated responsive to the error conditions. The apparatus includes an extracorporeal blood processing system, at least one sensor that senses the presence or absence of gas or monitors venous pressure, and a controller operably coupled to the blood processing system to selectively reduce pump speed or to reconfigure flow paths within the blood processing system responsive to the sensor output.Type: ApplicationFiled: September 12, 2005Publication date: January 12, 2006Applicant: Cardiovention, Inc.Inventors: A. Litzie, Steven Stringer, Mehrdad Farhangnia, Muslim Tyebjee, Thomas Afzal, Ben Brian
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Publication number: 20050256442Abstract: A tubing set for use with a blood handling system is described that decreases the priming volume and surface area of the blood handling circuit, lowering the risk of hemodilution, platelet activation, and hemolysis. The tubing set also reduces the number of manual connections required, and uses quick-disconnect couplings to facilitate connections between the various lines, and between the lines and the arterial and venous cannulae.Type: ApplicationFiled: May 6, 2005Publication date: November 17, 2005Applicant: Cardiovention, Inc.Inventors: Thomas Rawles, A. Litzie, David Fallen, Steven Stringer
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Patent number: 6960322Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: GrantFiled: July 8, 2003Date of Patent: November 1, 2005Assignee: Cardiovention, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Ben F. Brian, III, Fred I. Linker, James M. Culp, Jean-Pierre Dueri, Thomas A. Afzal
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Patent number: 6890316Abstract: A tubing set for use with a blood handling system is described that decreases the priming volume and surface area of the blood handling circuit, lowering the risk of hemodilution, platelet activation, and hemolysis. The tubing set also reduces the number of manual connections required, and uses quick-disconnect couplings to facilitate connections between the various lines, and between the lines and the arterial and venous cannulae.Type: GrantFiled: April 25, 2002Date of Patent: May 10, 2005Assignee: Cardiovention, Inc.Inventors: Thomas A. Rawles, A. Kenneth Litzie, David M. Fallen, Steven K. Stringer
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Publication number: 20040228760Abstract: Apparatus and methods for removing gas from a blood handling system. A filter apparatus for monitoring and removing gas is provided comprising of a gas removal/blood filter, a sensor to sense the presence of gas, and a valve operably coupled to the sensor to evacuate gas from the apparatus when the sensor detects an accumulation of gas. When used with a previously known blood handling system, the present filter apparatus facilitates priming and the addition of additional blood handling elements during operation of the blood handling system.Type: ApplicationFiled: June 21, 2004Publication date: November 18, 2004Applicant: Cardiovention, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Fred I. Linker, Ben F. Brian
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Patent number: 6773670Abstract: Apparatus and methods for removing gas from a blood handling system. A filter apparatus for monitoring and removing gas is provided comprising of a gas removal/blood filter, a sensor to sense the presence of gas, and a valve operably coupled to the sensor to evacuate gas from the apparatus when the sensor detects an accumulation of gas. When used with a previously known blood handling system, the present filter apparatus facilitates priming and the addition of additional blood handling elements during operation of the blood handling system.Type: GrantFiled: February 5, 2002Date of Patent: August 10, 2004Assignee: CardioVention, Inc. c/o The Brenner Group, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Fred I. Linker, Ben F. Brian, III
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Patent number: 6730267Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: GrantFiled: February 9, 2001Date of Patent: May 4, 2004Assignee: Cardiovention, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Ben F. Brian, III, Fred I. Linker, James M. Culp, Jean-Pierre Dueri, Thomas A. Afzal
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Patent number: 6689315Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system and a pump impeller with a single piece metal insert. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: GrantFiled: April 5, 2002Date of Patent: February 10, 2004Assignee: Cardiovention, Inc.Inventors: Fred I. Linker, Jean-Pierre Dueri, Paul LaRoy Edwards, Ronald Cambron, Ben F. Brian, III
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Publication number: 20040009097Abstract: Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.Type: ApplicationFiled: July 8, 2003Publication date: January 15, 2004Applicant: CardioVention, Inc.Inventors: Steven K. Stringer, Kevin L. Hultquist, Mehrdad Farhangnia, Ben F. Brian, Fred I. Linker, James M. Culp, Jean-Pierre Dueri, Thomas A. Afzal
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Patent number: 6503450Abstract: Improvements to integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood are provided. An inner member arranged along a central axis of the device accelerates blood entering the fiber bundle to reduce microbubble generation and blood trauma. Shearing loads imposed on the fiber elements of the fiber bundle are reduced by the addition of a reinforcement structure, while the gas flow path is configured to reduce flooding and loss of oxygenation efficiency due to occasional rupture of fiber elements.Type: GrantFiled: December 30, 1999Date of Patent: January 7, 2003Assignee: Cardiovention, Inc.Inventors: Thomas A. Afzal, Jean-Pierre Dueri, Alex Leynov, Anthony Makarewicz, Alec A. Piplani, Greg Potts
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Patent number: 6454999Abstract: An integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood is provided that includes a plurality of partitions disposed within or about the fiber bundle assembly to lengthen the flow path of blood passing through the fiber bundle. Alternatively, or in addition, blood flow paths may be lengthened and oxygenation improved by providing internal recirculation paths within the pump/oxygenator, which also advantageously may be used to reduce blood trauma caused by stagnation nearing moving parts and heat build-up.Type: GrantFiled: October 29, 1999Date of Patent: September 24, 2002Assignee: Cardiovention, Inc.Inventors: Mehrdad Farhangnia, Alex Leynov, Joseph Loeffler, Alec A. Piplani, Greg Potts, Christian Skieller
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Patent number: 6428747Abstract: An integrated blood pump, oxygenator and heat exchanger is provided having a rotating hollow fiber bundle assembly. A plurality of vanes arranged along a central shaft of the device increase pressure near the center of the fiber bundle to develop sufficient pressure head to pump the blood through the heat exchanger. In alternative embodiments, the heat exchanger comprises a pleated metal wall, a bundle of non-permeable hollow fibers, or a coiled tub disposed between the rotating hollow fiber bundle and an interior wall of the housing.Type: GrantFiled: October 29, 1999Date of Patent: August 6, 2002Assignee: Cardiovention, Inc.Inventors: Jean-Pierre Dueri, Robert Jochim, Alex Leynov
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Patent number: 6387323Abstract: An integrated blood oxygenation and pump system suitable for use in a sterile field having a low priming volume is provided in which a blood oxygenator portion of the system includes an active element, separate from the pump, that disrupts the development of laminar flow and stagnation zones in the fiber bundle employed for gas exchange. The integrated system enables the pump and oxygenator to be used independently of one another or be rapidly reconfigured to provide both pumping action and blood oxygenation.Type: GrantFiled: May 15, 1998Date of Patent: May 14, 2002Assignee: Cardiovention, Inc.Inventors: Thomas A. Afzal, Ronald G. Williams
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Patent number: 6379618Abstract: Improvements to integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood are provided. A plurality of vanes arranged along a central shaft of the device increase pressure near the center of the fiber bundle to prevent microbubble generation and blood trauma. Shearing loads imposed on the fiber elements of the fiber bundle are reduced by the addition of a reinforcement structure, while the gas flow path is configured to minimize flooding and loss of oxygenation efficiency due to occasional rupture of fiber elements. Blood trauma may be further reduced by contouring the vanes and other components of the device.Type: GrantFiled: December 30, 1998Date of Patent: April 30, 2002Assignee: Cardiovention, Inc.Inventors: Alec A. Piplani, Anthony Makarewicz, Jean-Pierre Dueri, Thomas A. Afzal