Abstract: The present invention concerns an image conversion module (09) that comprises an optical interface (10) for establishing an optical path (07). The image conversion module (09) further comprises a beam splitting element (13) on the optical path (07). The beam splitting element (13) is configured for splitting a beam entering the optical interface (10, 11) on the optical path (07) into a first optical subpath (14) and a second optical subpath (16). The image conversion module (09) further comprises a microelectromechanical optical system (17) that is configured for enhancing a depth of field on the first optical subpath (14) that is directed to a first optoelectronic submodule (21). The image conversion module (09) further comprises a second optoelectronic submodule (24) having an electronic sensor (26) on the second optical subpath (16). The second optoelectronic submodule (24) is configured for acquiring additional data on the sample (02).

Abstract: One embodiment of the present invention is a visual field tester that includes: (a) a projection screen; (b) a stimulus projection system that projects a light source onto a first side of the projection screen; (c) a background projection system that projects a background light onto the first side of the projection screen; and (d) a magnifier lens system disposed on a second side of the projection screen that directs light transmitted through the projection screen to a predetermined location.

Abstract: One embodiment of the present invention is a visual field tester that includes: (a) a projection screen; (b) a stimulus projection system that projects a light source onto a first side of the projection screen; (c) a background projection system that projects a background light onto the first side of the projection screen; and (d) a magnifier lens system disposed on a second side of the projection screen that directs light transmitted through the projection screen to a predetermined location.

Abstract: One embodiment of the present invention is an optical delay line that comprises a plurality of optical elements in optical communication with each other, wherein: (a) at least one of the plurality of optical elements is capable of spatially dispersing a spectrum of an optical signal to provide a spatially dispersed optical signal; (b) at least one of the plurality of optical elements is adjustable to affect one or more of a phase delay and a group delay of an optical signal; and (c) at least one of the plurality of optical elements compensates for polarization introduced into the optical signal by others of the optical elements.

Abstract: One embodiment of the present invention is a visual field tester that includes: (a) a high intensity light source; (b) an optical fiber; (c) scanning optics, wherein light output from the light source is directed by the optical fiber to impinge upon the scanning optics, and the scanning optics directs the light to form a stimulus at various field positions; and (d) a video display system to output one or more light patterns. Another embodiment of the present invention is a visual field tester that includes: (a) a video display system to output one or more types of light patterns; (b) a background illumination display system; and (c) viewing optics to magnify the field of view of the video display system and the background illumination display system.

Abstract: One embodiment of the present invention is an optical path length scanner which includes: (a) a set of prisms mounted evenly along a movable carrier; and (b) a mechanism that drives the movable carrier to move.

Abstract: Wavefront refractor apparatus and method which records two Hartmann-Shack images simultaneously at different distances from the lenslet array. The two images recorded this way enable each focal spot to be associated with a lenslet forming the spot to identify “bad” spots, “ghost” spots, and to provide more accurate measurements for diverging or converging wavefronts.

Abstract: Embodiments of the present invention provide method and apparatus for measuring a wavefront of a beam of radiation. In particular, one embodiment of the present invention is an apparatus for measuring a wavefront of a beam of radiation at a first plane which includes: (a) relay optics adapted to relay the wavefront from the first plane to a second plane; (b) a moving boundary locus apparatus disposed between the first and second planes; (c) a two-dimensional photodetector array comprising—at least 4×4 photodetector elements disposed in the second plane, wherein each photodetector element produces a time varying signal in response to movement of a portion of the moving boundary locus apparatus; (d) a synchronizer adapted to synchronize each of the time varying signals with a position of the portion of the moving boundary locus apparatus; and (e) an analyzer, responsive to synchronized time varying signals output from the synchronizer, to measure the wavefront of the beam.

Abstract: Method and apparatus is disclosed for mapping a corneal contour and thickness profile. In accordance with one aspect of the present invention, a set of narrow, collimated, parallel beams is projected onto a corneal surface at an angle with respect to a predetermined axis (“an instrument axis”) that is substantially aligned with a visual axis of an eye. The set of beams is rotated about the instrument axis. A CCD camera is disposed to view the cornea along the instrument axis. Traces of the rotating set of beams form a set of rings in images obtained by the CCD camera; wherein outer and inner edges of the rings correspond to intersections of the set of beams with anterior and posterior surfaces of the cornea, respectively. Next, a direct triangulation algorithm is used to determine spatial positions of data points along the outer edges of the rings, and these spatial positions are used to reconstruct the anterior surface profile of the cornea.

Abstract: Embodiments of the present invention advantageously satisfy the above-identified need in the art, and provide method and apparatus for measuring refractive errors of an eye that improve upon wavefront type refractors using a conventional Hartmann-Shack sensor. Specifically, one embodiment of the present invention is an apparatus for measuring refractive errors of an eye which includes: (a) a source of a probe beam; (b) a first Badal lens system adapted to project the probe beam into a subject's eye to form an illumination spot on a retina; (c) a second Badal lens system adapted to image the illumination spot onto an image plane substantially conjugate to the retina; and (d) a spatial filter disposed in the image plane adapted to transmit at least a portion of the image.

Abstract: One embodiment of the present invention is an optical coherence tomography (“OCT”) application apparatus that performs an OCT application on an object. The OCT application apparatus includes: (a) an OCT scanning apparatus which outputs a beam of OCT scanning radiation; (b) an active tracking system that generates and projects a beam of tracking radiation onto a region including a reference tracking feature, which active tracking system includes a tracking optical system that is disposed to intercept the beam of tracking radiation and the beam of OCT scanning radiation; and (c) wherein the active tracking system analyzes tracking radiation reflected from the region to detect movement of the object, and to generate a tracking signal which directs the tracking optical system to follow the movement of the object. In one embodiment of the present invention, the OCT application comprises forming an OCT scan image of the object, for example and without limitation, a retina of an eye.

Abstract: Embodiments of the present invention provide method and apparatus for diagnosing and monitoring eye disease such as, for example, glaucoma. In particular, embodiments of the present invention analyze OCT scans of a retina to determine one or more of the following measures for diagnosing and monitoring glaucomatous retinal nerve fiber layer (“NFL”) change: an NFL thickness; a ratio of NFL thickness in a vertical quadrant (superior and inferior quadrants in an OCT scan are combined in a vertical average) and a horizontal quadrant (nasal and temporal quadrants in the OCT scan are combined in a horizontal average); and an NFL signal ratio (“NSR”) of a sum of signal strengths in a predetermined portion of the NFL and a sum of signal strengths in a predetermined region below a retina-pigment epithelium (“RPE”) interface.

Abstract: An embodiment of the present invention is an apparatus to determine position of an eye that includes: (a) two off-axis, radiation emitter-photodetector pairs, wherein an emitter of a pair is disposed to transmit radiation toward the eye and a photodetector of the pair is disposed to receive radiation reflected by the eye; and (b) a controller that analyzes output from the photodetectors to determine the position of the eye.

Abstract: A visual field tester which measures the visual field of a patient's eye, which visual field tester includes: (a) an optical radiation source having an entrance pupil plane, which optical radiation source outputs one or more spots of optical radiation; and (b) an optical relay system which relays a point in the entrance pupil plane or a point conjugate to the point in the entrance pupil plane to the patient's eye with a one-to-one magnification, wherein the optical relay system comprises a beamsplitter disposed at an angle with respect to a retroreflector array.

Abstract: Embodiments of the present invention are method and apparatus for simply and economically providing efficient scanning in an optical coherence tomography ("OCT") apparatus.

Abstract: Ophthalmologic surgical microscope which is combined internally with an optical coherence tomography ("OCT") apparatus wherein auto-focusing is provided by driving a motorized internal focusing lens of the ophthalmologic surgical microscope with a signal output from the OCT apparatus. An embodiment of the inventive ophthalmologic surgical microscope includes: (a) an optical coherence tomography ("OCT") apparatus; (b) a beamcombiner for internally coupling output from the OCT apparatus into the ophthalmologic surgical microscope; and (c) a motor for moving an internal focusing lens of the ophthalmologic surgical microscope in response to a signal from the OCT apparatus, whereby the ophthalmologic surgical microscope is auto-focused.

Abstract: Embodiments of the present invention are method and apparatus for simultaneously measuring the length and refractive error of an eye, preferably in a non-contact mode. In particular, an embodiment of the present invention is an apparatus which measures length and refractive error of an eye which includes: (a) a source of short coherence radiation which couples radiation into a Michelson interferometer, the arms of the Michelson interferometer having a predetermined optical pathlength difference; (b) an injector which couples radiation output from the interferometer into the eye; and (c) a relay system which couples radiation output from the eye to a spectrometer; wherein the spectrometer measures displacement of radiation to measure the refractive error and the spectrometer measures density of fringes to measure the length.

Abstract: An embodiment of the present invention is a refractively corrected, wavelength selective, transparent visual field test occluder for a non-tested eye used in a visual field testing apparatus which uses a stimulus that produces light in a first color spectral range and a background illumination that produces light in a second color spectral range, the visual field test occluder comprising: (a) a base; (b) a fastener configured to fasten the base over a subject's eye; (c) a mounting affixed to the base configured to hold a filter and a refractive lens; and (d) a filter held in the mounting; wherein the filter substantially prevents transmission of light in the first color spectral range and substantially transmits light in the second color spectral range.

Abstract: Embodiments of the present invention provide method and apparatus for use during a neurosurgical procedure to enable a multi-coordinate manipulator ("MCM") to locate blood vessels and nerves in a patient's brain with submillimeter resolution. In addition, embodiments of the present invention provide method and apparatus for mapping oxygenation of brain tissue in three dimensions to differentiate tumor tissue from normal brain tissue with submillimeter resolution.

Abstract: Embodiments of the present invention are method and apparatus for measuring the size and position of an eye's pupil, and for doing so rapidly. In particular, embodiments of the present invention are methods and apparatus for determining pupil size and position without measuring the fall pupil and for doing so rapidly, in real time, as data are being collected.