Abstract: A computer-implemented method for locating possible artifacts in a virtually stained histology image, which was obtained from an initial histology image, is provided. In the method, at least one further image is generated on the basis of the virtually stained histology image or the initial histology image. The differences between the at least one further image and the virtually stained histology image are determined when the at least one further image has been generated on the basis of the initial histology image or the differences between the at least one further image and the initial histology image are determined when the at least one further image has been generated on the basis of the virtually stained histology image, and a mapping from the determined differences to their positions in the virtually stained histology image is created. The positions in the virtually stained histology image represent the positions of possible artifacts.

Abstract: Provided is to a system with an interface for providing visualization data for visualizing at least one section of a patient's eye, comprising an OCT device for capturing OCT scanning data by scanning the section of the patient's eye by means of an OCT scanning beam and comprising a computer unit for processing the OCT scanning data into the visualization data within the scope of an image rectification algorithm, which is designed to output the visualization data at the interface.

Abstract: A stand for a surgical microscope includes a first stand part including a first bearing and a second bearing, a shaft arranged in the first bearing and defining a rotation axis, a second stand part fixedly connected to the shaft, mounted on the first stand part together with the shaft pivotably about the rotation axis, and including a force transmission point, a lever part mounted on the second stand part at the force transmission point, arranged pivotably about the rotation axis, and including a third bearing, and a torque compensation assembly applying a counter torque to the second stand part to compensate a load torque including a dynamic load torque occurring when the second stand part is pivoted about the rotation axis and a static load torque resulting from a gravitation force acting on the second stand part and on elements mounted on the second stand part.

Abstract: An optical assembly for a surgical microscope includes an iris diaphragm assembly arranged in a first plane and including a first adjustable diaphragm arranged in a first observation beam path of the surgical microscope and defining a first opening, and a second adjustable diaphragm arranged in a second observation beam path of the surgical microscope and defining a second opening, an optical wheel rotatably mounted on the iris diaphragm assembly in a second plane, the optical wheel including openings for receiving optical elements and optical element holders fastened to the optical wheel to secure the optical elements in the openings without creating transverse forces on the optical elements, the optical wheel having substantially a shape of a half wheel and including an external gearing provided on a circular portion of the optical wheel. A surgical microscope includes the optical assembly with the iris diaphragm assembly and the optical wheel.

Abstract: Provided is a controller for an electrical drive unit—which drives a treatment needle—of an ophthalmosurgical handpiece, comprising a generator unit, which provides a control variable with control oscillation, wherein the control oscillation has a first oscillation component at a first control frequency, wherein the first oscillation component is settable depending on a first ratio of a mechanical deflection amplitude of the treatment needle to the electrical control variable at the first control frequency. It is proposed that the generator unit is configured to provide the control oscillation of the control variable with at least one further oscillation component at a further control frequency, different than any other control frequency, in such a way that the further oscillation component is settable depending on a further ratio of the mechanical deflection amplitude of the treatment needle to the electrical control variable at the respective further control frequency.

Abstract: The present invention relates to an eye surgery method and an eye surgery system. An eye surgery method comprises directing illumination light direction onto a target object of an eye; generating an observation image from observation light emerging from the target object due to scattering of the illumination light at the target object; highlighting, in the observation image, a region of interest characterized by a specific wavelength range by modifying the observation light or by modifying digital raw image data representing a spatial intensity distribution of the observation light; and identifying the target object in the observation image including the highlighted region of interest and manipulating at least one part of the identified target object.

Abstract: A method for controlling the illumination of ophthalmological devices which operate in an observation mode and a recording mode. The method adapts the illuminance from ophthalmological devices which include an observation mode and a recording mode and the illuminance therefrom being increased above a specified value for the radiant flux ?soll for the duration of the recording mode. According to the invention, the illuminance is increased to a radiant flux above the specified value ?soll for the recording mode and lowered to a radiant flux below the specified value for the radiant flux ?soll for a specified period of time after the recording mode has finished. Although the proposed method for adapting the illuminance is provided for slit lamp microscopes, it can be used for any ophthalmological device that has both an observation mode and a recording mode to obtain high-quality, well-lit recordings in the recording mode.

Abstract: A method of preparing an apparatus for material processing by generating optical breakthroughs in an object. The apparatus includes a variable focus adjustment device. A contact element is mounted to the apparatus, the contact element has a curved contact surface having a previously known shape. The position of the contact surface is determined prior to processing the object, by focusing measurement laser radiation near or on the surface by the variable focus adjustment device, and the focus position is adjusted in a measurement surface intersecting the expected position of the contact surface. Radiation from the focus of the measurement laser radiation is confocally detected. The position of points of intersection between the measurement surface and the contact surface is determined from the confocally detected radiation to determine the position of the contact surface from the position of the points of intersection and the previously known shape of the contact surface.

Abstract: A method for acquiring data with the aid of a surgical microscopy system comprises recording a data set having a multiplicity of images and deciding whether or not the new data set ought to be stored in a data memory of a database. The decision is taken by an existing classifier. A new classifier is determined on the basis of training data which comprise the data sets stored in the data memory of the database and/or comprise data obtained from the data sets stored in the data memory of the database. The new classifier is then used instead of the existing classifier when deciding whether a subsequently recorded new data set ought to be stored.

Abstract: An apparatus for producing incisions in an interior of an eye. For example, the apparatus includes an image recording device that records at least part of the image field and an image evaluation device that evaluates recordings of the image recording device and produces signals for the control device and/or the operator. Furthermore, the invention relates to a method for producing incisions in the interior of an eye, wherein an image recording device is used to record at least part of the image field and an image evaluation device evaluates the recordings of the image recording device and produces signals for the control device and/or the operator.

Abstract: A method for acquiring annotated data with the aid of surgical microscopy systems comprises obtaining desired criteria which are intended to be satisfied by desired data to be annotated, and storing the set of desired criteria in a plurality of surgical microscopy systems. In each surgical microscopy system, images are then recorded and current criteria which correspond to the recorded images are determined. The current criteria are compared with the desired criteria. If the desired criteria sufficiently correspond to the current criteria, a confirmation is requested from a user as to whether said user would like to annotate data. If the user provides the confirmation, annotations for images are received from the user and stored together with the images.

Abstract: A-confocal, interferometric measuring arrangement, a spatially resolving detector, apparatuses for positioning purposes and an evaluation unit. A beam splitter serves to output couple and image on the spatially resolving detector some of the light signal reflected by the cornea, upstream of which detector a reference light source with a delay line and a beam splitter are arranged in order to realize a superposition of the part of the light signal reflected by the cornea, to be imaged on the spatially resolving detector with a reference signal. The evaluation unit is determines the topography of the cornea from the simultaneously recorded signals of the interferometric measuring arrangement and the spatially resolving detector. The proposed solution combines a confocal FD OCT method with elements of imaging holoscopy and can thereby interferometrically measure the topography of the cornea with the necessary accuracy.

Abstract: A planning device generating control data for a treatment apparatus for cornea transplantation using a laser device to separate a corneal volume by at least one cut surface in the cornea and to separate a transplant, from a surrounding transplantation material by at least one cut surface, wherein the planning device includes an interface supplying measurement data relating to parameters of the cornea. A computer defines a corneal cut surface which confines the corneal volume to be removed, and determines a transplant cut surface by using the transplantation material data and depending on the defined corneal cut surface. The transplant cut surface confines the transplant, and the computer generates one control data for each cut surface to control the laser, wherein the respective cut surfaces can be produced by the laser to isolate the corneal volume and the transplant and to make them removable.

Abstract: A screen (3) for an HMD (1) is provided, and may be designed as a display screen or as a projection screen. The screen (3) comprises a layer (19) of a material with a switchable degree of transparency and at least one further switchable layer (17, 21, 23) which, in dependence on the switching state, can assume at least two physical states, the physical states differently influencing at least one optical property of light passing through the switchable layer or reflected by it.

Abstract: An ophthalmic surgical microscope includes a main objective lens, through which an observation beam path passes, and a confocal optical system configured as a refractometer to determine the refraction of an eye. The optical system includes a measurement light source to generate a measurement light beam, a light detector to measure an intensity of measurement light and an optical unit to direct the measurement light beam onto the retina of the eye and to return measurement light reflected back at the retina to the light detector. The optical system includes an adaptive optical module (AOM) to modify a wavefront of the measurement beam path such that an intensity of the back-reflected measurement light changes. A spherical equivalent (SE) of the ametropia of the eye is determined based on a setting of the AOM, at which the measured intensity of the back-reflected measurement light has a maximum.

Abstract: A microscopy method for imaging an object includes: imaging the object into an optical image onto an image detector, generating electronic image data from the optical image using the image detector and generating an electronic image from the electronic image data, defining a region of interest in the electronic image, determining a depth distribution in the region of interest and/or in a region of the object corresponding to the region of interest, determining a desired depth region in the depth distribution, selecting at least one imaging parameter with which a size of a depth-of-field region can be changed, and setting the depth-of-field region of the electronic image by changing the at least one selected imaging parameter such that the depth-of-field region covers the desired depth region or covers a specific portion thereof.

Abstract: A computer-implemented method determines a geometric feature of a section of a blood vessel in an operating region. An image of the section is provided. An adapted blood vessel model is provided via image processing for the section by adapting a blood vessel model, which describes the section as a flow channel with a wall delimiting the latter and with an axis of symmetry. A centerline of the section of the blood vessel is determined as a contiguous pixel line. A relative spatial position of the side of the wall is ascertained based on the centerline and the image provided. The geometric feature is derived from the adapted blood vessel model. The disclosure also relates to a method for determining the length of a contiguous pixel line in an image and a system for determining a geometric feature of a section of an object.