Patents Assigned to Carle Development Foundation
  • Polypeptides useful for appetite suppression
    Patent number: 7544662
    Abstract: The present invention relates to polypeptides obtained from bear derivative isolate which are useful in suppressing appetite. The polypeptides of the present invention are most preferably between 12 and 13 amino acid residues in length and a mass of about 1249. The present invention also relates to a method of treating obesity by administering to obese subjects an effective amount of the polypeptides of the present invention.
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: June 9, 2009
    Assignee: Carle Development Foundation
    Inventors: Ralph A. Nelson, James D. Shoemaker
  • Bear derived isolate and method
    Patent number: 7060300
    Abstract: A bear derived isolate found in denning black bears or black bears from which food has been withheld for at least two weeks when injected into another mammal produces reduced heart rate, reduced respiratory rate, reduced temperature, and a wakeful tranquility not unlike the phenomena of the denning black bear. The isolate is taken from either the serum or urine of such denning bear. The method of the invention involves the steps of fractionating the serum or urine of a denning black bear to produce fractions of varying potency.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: June 13, 2006
    Assignee: Carle Development Foundation
    Inventors: Ralph A. Nelson, Patricia G. Miers, Kenneth L. Rinehart
  • Bear derived isolate and method
    Patent number: 6855337
    Abstract: A bear derived isolate found in denning black bears or black bears from which food has been withheld for at least two weeks when injected into another mammal produces reduced heart rate, reduced respiratory rate, reduced temperature, and a wakeful tranquility not unlike the phenomena of the denning black bear. The isolate is taken from either the serum or urine of such denning bear. The method of the invention involves the steps of fractionating the serum or urine of a denning black bear to produce fractions of varying potency.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: February 15, 2005
    Assignee: Carle Development Foundation
    Inventors: Ralph A. Nelson, Patricia G. Miers, Kenneth L. Rinehart