Abstract: Isoindoline derivatives are disclosed, as for instance of the formula: ##STR1## and methods of preparation of these compounds, such as the reaction of o-cyano-benzylbromide with a compound of formula ##STR2## and subsequent saponification. The compounds possess analgesic and anti-inflammatory activity.
Type:
Grant
Filed:
January 28, 1977
Date of Patent:
October 3, 1978
Assignee:
Carlo Erba
Inventors:
PierNicola Giraldi, Giuliano Nannini, Willy Logemann, Raffaele Tommasini, Ada Buttinoni, Giovanni Biasoli
Abstract: Composition and method for the prevention and treatment of syndromes caused by platelet-aggregation disorders wherein the active ingredient is a compound of the formula: ##STR1## wherein R is H or C.sub.1 -C.sub.4 alkyl and R.sub.1 is H, C.sub.1 -C.sub.4 alkyl or ##STR2## wherein n is 1 or 2, and R.sub.2 and R.sub.3 are H or C.sub.1 -C.sub.4 alkyl, or salts thereof.
Type:
Grant
Filed:
October 16, 1975
Date of Patent:
March 1, 1977
Assignee:
Carlo Erba
Inventors:
Pier Nicola Giraldi, Giuliano Nannini, Giovanni Riasoli, Anna Spelta, Aurelio Contone