Patents Assigned to Carmel-Haifa University Economic Corp. Ltd.
  • Patent number: 11628187
    Abstract: A conditioned cell culture medium of cells derived from Spalax or naked mole rat (Heterocephalus glaber) and methods for preparing it are provided. Pharmaceutical compositions comprising the conditioned cell culture medium and its use in the treatment of cancer as well as methods for identifying anti-cancer agents are also provided.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: April 18, 2023
    Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.
    Inventors: Aaron Avivi, Imad Shams, Irena Manov
  • Patent number: 10676747
    Abstract: An active agent capable of reducing quinone reductase 2 activity is for use in improvement of cognition in a subject. Such an active agent can be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A pharmaceutical composition can contain the active agent or a vector containing the active agent.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: June 9, 2020
    Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.
    Inventors: Kobi Rosenblum, Akiva Rappaport
  • Patent number: 10491374
    Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes a key table generator configured to generate random values based on a seed value and generate a key table including the generated random values; and an encryptor configured to apply the generated key table to a round function, generate a block encryption algorithm having a Feistel structure based on the round function, and encrypt a plaintext data block based on the generated block encryption algorithm.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: November 26, 2019
    Assignees: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITY
    Inventors: Duk-Jae Moon, Ji-Hoon Cho, Kyu-Young Choi, Nathan Keller, Orr Dunkelman, Itai Dinur
  • Patent number: 10411880
    Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes, a key table generation unit configured to generate random values derived from a seed value and generate a key table including the generated random values, and an encryption unit configured to encrypt a plain text data block by generating an encryption algorithm by repeatedly combining the generated key table with a permutation function in a crossing manner, and using the generated encryption algorithm.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: September 10, 2019
    Assignees: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITY
    Inventors: Duk-Jae Moon, Ji-Hoon Cho, Kyu-Young Choi, Nathan Keller, Orr Dunkelman, Itai Dinur
  • Patent number: 10246712
    Abstract: A method for improving a cognitive function in a subject comprising administering to said subject an active agent reducing PKR-like endoplasmic reticulum kinase (PERK) activity is provided.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: April 2, 2019
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Kobi Rosenblum, Vijendra Sharma, Hadile Ounallah Saad
  • Patent number: 10113171
    Abstract: An active agent capable of reducing quinone reductase 2 activity, for use in improvement of cognition in a subject is provided. Such an active agent may be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A vector comprising a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 and a pharmaceutical composition comprising an active agent capable of reducing quinone reductase 2 activity or said vector are provided as well.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: October 30, 2018
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Kobi Rosenblum, Akiva Rappaport
  • Publication number: 20170126395
    Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes, a key table generation unit configured to generate random values derived from a seed value and generate a key table including the generated random values, and an encryption unit configured to encrypt a plain text data block by generating an encryption algorithm by repeatedly combining the generated key table with a permutation function in a crossing manner, and using the generated encryption algorithm.
    Type: Application
    Filed: February 23, 2016
    Publication date: May 4, 2017
    Applicants: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITY
    Inventors: Duk-Jae MOON, Ji-Hoon CHO, Kyu-Young CHOI, Nathan KELLER, Orr DUNKELMAN, Itai DINUR
  • Publication number: 20170126396
    Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes a key table generator configured to generate random values based on a seed value and generate a key table including the generated random values; and an encryptor configured to apply the generated key table to a round function, generate a block encryption algorithm having a Feistel structure based on the round function, and encrypt a plaintext data block based on the generated block encryption algorithm.
    Type: Application
    Filed: December 28, 2015
    Publication date: May 4, 2017
    Applicants: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITY
    Inventors: Duk-Jae MOON, Ji-Hoon CHO, Kyu-Young CHOI, Nathan KELLER, Orr DUNKELMAN, Itai DINUR
  • Publication number: 20140248371
    Abstract: A conditioned cell culture medium of cells derived from Spalax or naked mole rat (Heterocephalus glaber) and methods for preparing it are provided. Pharmaceutical compositions comprising the conditioned cell culture medium and its use in the treatment of cancer as well as methods for identifying anti-cancer agents are also provided.
    Type: Application
    Filed: January 9, 2014
    Publication date: September 4, 2014
    Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.
    Inventors: Aaron Avivi, Imad Shams, Irena Manov
  • Publication number: 20140234826
    Abstract: System and method for improving reading speed and comprehension of a user that use a special software application operable through a computer processor. The method and system are configured for receiving personal details and reading level of the user; setting initial presentation pace and acceleration rate; presenting textual content over a computer screen, selected according to the received reading level and personal details; determining a current presentation pace according to the initial presentation pace and acceleration rate at each given timeframe; and manipulating presentation of text parts of the presented textual content at each given timeframe, according to the current presentation pace. The manipulation is done by erasing or blurring these text parts at a rate that corresponds to the current presentation pace.
    Type: Application
    Filed: March 6, 2014
    Publication date: August 21, 2014
    Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.
    Inventor: Zvia Breznitz
  • Patent number: 8799289
    Abstract: The present invention provides an electronic documents management system and method for classifying, publishing, searching and locating electronic documents. Electronic documents are classified and published via an ontological description consisting of at least one vector, each vector comprising at least one feature-value pair. Each vector's slot corresponds to a feature and the vector's range of each slot corresponds to the set of all possible values of each feature. In order to classify an electronic document, two hashing functions are applied. A first hashing function maps each feature to a slot number, corresponding to a coordinate in the appropriate vector. A second hashing function maps the value of each pair to a numeric value of a slot, corresponding to the range of each coordinate. The result of the two hashing functions is an ordered vector that can be mapped to a node in hypercube.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: August 5, 2014
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Yosef Ben Asher, Shlomo Berkovsky
  • Publication number: 20130236447
    Abstract: Inhibition of eIF-2? phosphorylation can be used to improve cognitive function and/or to treat dementia, including Alzheimer's Disease. In particular, this can be achieved by inhibiting the kinase activity of PKR in a non-toxic manner.
    Type: Application
    Filed: December 17, 2012
    Publication date: September 12, 2013
    Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP., LTD.
    Inventors: Yaacov ROSENBLUM, Elad STERN, Yifat SEGEV
  • Patent number: 8093031
    Abstract: The invention relates to novel heparanases, heparanase splice variants, and to polynucleotides encoding them. Particularly, the invention relates to Spalax heparanases, and to Spalax and human heparanase splice variants. Heparanase splice variants can be used, for example, to modulate the activity of heparanase in diseases disorders or conditions caused by or associated with the enzymatic activity of heparanase. For instance, a splice variant capable of down regulating the activity of heparanase can be used to treat primary tumors and/or to prevent or treat metastasis.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: January 10, 2012
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Nicola J. Nasser, Aaron Avivi, Israel Vlodavsky, Eviatar Nevo
  • Patent number: 8044190
    Abstract: The present invention provides a MAP kinase homologue gene, designated EhHOG, isolated from Eurotium herbariorum, a common fungal species from the extreme hypersaline environment of the Dead Sea, capable of improving tolerance of plants and other organisms to abiotic stresses such as osmotic, heat, dehydration, freezing-thawing, oxidative and salinity stress.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: October 25, 2011
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Eviatar Nevo, Yan Jin, Weining Song
  • Publication number: 20110257988
    Abstract: A medical diagnosis decision support system for assisting a health professional to diagnose a medical condition. The system is first provided with an anchor condition that can be a symptom, a sign, a laboratory test result, or an imaging test results or any combination thereof The system then guides users in a series of predetermined phases regarding abstract or concrete diagnosis groups that should be considered and appropriate data that should be collected during the clinical investigation process. The system suggests history and physical examination clinical data items, laboratory, and imaging tests that should be collected in order to differentiate among alternative diagnoses. In each phase, possible diagnoses are listed and ranked.
    Type: Application
    Filed: April 14, 2010
    Publication date: October 20, 2011
    Applicants: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD., MOR RESEARCH APPLICATIONS LTD.
    Inventors: Yaron DENEKAMP, Mor Peleg
  • Publication number: 20110052566
    Abstract: Inhibition of eIF-2? phosphorylation can be used to improve cognitive function and/or to treat dementia, including Alzheimer's Disease. In particular, this can be achieved by inhibiting the kinase activity of PKR in a non-toxic manner.
    Type: Application
    Filed: June 30, 2010
    Publication date: March 3, 2011
    Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP., LTD.
    Inventors: Yaacov Rosenblum, Elad Stern, Yifat Segev
  • Patent number: 7738402
    Abstract: A method for organizing a plurality of communication devices of an ad hoc communication system into a communication network. The devices are organized into one or more communication graphs where at least one of the graphs is a rooted tree. The invention also provides an ad hoc communication system wherein the devices are organized into one or more communication graphs, where at least one of the graphs is a rooted tree. A method for routing a communication session in the system is also provided where a session is routed from the calling node to the tree root and from the tree root to the called node. In a preferred embodiment, shortcuts are sought in the session route.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: June 15, 2010
    Assignee: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Sharoni Feldman, Yosi Ben Asher
  • Publication number: 20080098010
    Abstract: The present invention provides an electronic documents management system and method for classifying, publishing, searching and locating electronic documents. Electronic documents are classified and published via an ontological description consisting of at least one vector, each vector comprising at least one feature-value pair. Each vector's slot corresponds to a feature and the vector's range of each slot corresponds to the set of all possible values of each feature. In order to classify an electronic document, two hashing functions are applied. A first hashing function maps each feature to a slot number, corresponding to a coordinate in the appropriate vector. A second hashing function maps the value of each pair to a numeric value of a slot, corresponding to the range of each coordinate. The result of the two hashing functions is an ordered vector that can be mapped to a node in hypercube.
    Type: Application
    Filed: September 1, 2005
    Publication date: April 24, 2008
    Applicant: Carmel-Haifa University Economic Corp. Ltd
    Inventors: Yosef Ben Asher, Shlomo Berkovsky
  • Publication number: 20080019996
    Abstract: The invention relates to a method for treatment of chronic myelogenous leukemia (CML), Ph+ acute lymphoblastic leukemia (ALL), prostate cancer and ?-globin disorders such as sickle cell anemia and ?-thalassemia, comprising administration of a mycelium extract from at least one higher Basidiomycetes medicinal mushroom selected from the group consisting of Ganoderma adspersum, Hypsizygus ulmarium, Kuehneromyces mutabilis, Omphalotus olearius, Panus conchatus, Piptoporus betulinus, Pleurotus eryngii, and Trametes zonata.
    Type: Application
    Filed: August 20, 2007
    Publication date: January 24, 2008
    Applicants: Gavish-Galilee Bio Applications Ltd., Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Jamal MAHAJNA, Majed YASSIN, Solomon WASSER
  • Publication number: 20060153099
    Abstract: A method for organizing a plurality of communication devices of an ad hoc communication system into a communication network. The devices are organized into one or more communication graphs where at least one of the graphs is a rooted tree. The invention also provides an ad hoc communication system wherein the devices are organized into one or more communication graphs, where at least one of the graphs is a rooted tree. A method for routing a communication session in the system is also provided where a session is routed from the calling node to the tree root and from the tree root to the called node. In a preferred embodiment, shortcuts are sought in the session route.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 13, 2006
    Applicant: Carmel-Haifa University Economic Corp. Ltd.
    Inventors: Sharoni Feldman, Yosi Asher