Patents Assigned to Carmel-Haifa University Economic Corp. Ltd.
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Patent number: 11628187Abstract: A conditioned cell culture medium of cells derived from Spalax or naked mole rat (Heterocephalus glaber) and methods for preparing it are provided. Pharmaceutical compositions comprising the conditioned cell culture medium and its use in the treatment of cancer as well as methods for identifying anti-cancer agents are also provided.Type: GrantFiled: November 20, 2017Date of Patent: April 18, 2023Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.Inventors: Aaron Avivi, Imad Shams, Irena Manov
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Patent number: 10676747Abstract: An active agent capable of reducing quinone reductase 2 activity is for use in improvement of cognition in a subject. Such an active agent can be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A pharmaceutical composition can contain the active agent or a vector containing the active agent.Type: GrantFiled: October 29, 2018Date of Patent: June 9, 2020Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.Inventors: Kobi Rosenblum, Akiva Rappaport
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Patent number: 10491374Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes a key table generator configured to generate random values based on a seed value and generate a key table including the generated random values; and an encryptor configured to apply the generated key table to a round function, generate a block encryption algorithm having a Feistel structure based on the round function, and encrypt a plaintext data block based on the generated block encryption algorithm.Type: GrantFiled: December 28, 2015Date of Patent: November 26, 2019Assignees: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITYInventors: Duk-Jae Moon, Ji-Hoon Cho, Kyu-Young Choi, Nathan Keller, Orr Dunkelman, Itai Dinur
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Patent number: 10411880Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes, a key table generation unit configured to generate random values derived from a seed value and generate a key table including the generated random values, and an encryption unit configured to encrypt a plain text data block by generating an encryption algorithm by repeatedly combining the generated key table with a permutation function in a crossing manner, and using the generated encryption algorithm.Type: GrantFiled: February 23, 2016Date of Patent: September 10, 2019Assignees: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITYInventors: Duk-Jae Moon, Ji-Hoon Cho, Kyu-Young Choi, Nathan Keller, Orr Dunkelman, Itai Dinur
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Patent number: 10246712Abstract: A method for improving a cognitive function in a subject comprising administering to said subject an active agent reducing PKR-like endoplasmic reticulum kinase (PERK) activity is provided.Type: GrantFiled: October 27, 2016Date of Patent: April 2, 2019Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Kobi Rosenblum, Vijendra Sharma, Hadile Ounallah Saad
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Patent number: 10113171Abstract: An active agent capable of reducing quinone reductase 2 activity, for use in improvement of cognition in a subject is provided. Such an active agent may be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A vector comprising a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 and a pharmaceutical composition comprising an active agent capable of reducing quinone reductase 2 activity or said vector are provided as well.Type: GrantFiled: March 18, 2015Date of Patent: October 30, 2018Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Kobi Rosenblum, Akiva Rappaport
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Publication number: 20170126395Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes, a key table generation unit configured to generate random values derived from a seed value and generate a key table including the generated random values, and an encryption unit configured to encrypt a plain text data block by generating an encryption algorithm by repeatedly combining the generated key table with a permutation function in a crossing manner, and using the generated encryption algorithm.Type: ApplicationFiled: February 23, 2016Publication date: May 4, 2017Applicants: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITYInventors: Duk-Jae MOON, Ji-Hoon CHO, Kyu-Young CHOI, Nathan KELLER, Orr DUNKELMAN, Itai DINUR
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Publication number: 20170126396Abstract: Disclosed are an apparatus and a method for encryption. The apparatus includes a key table generator configured to generate random values based on a seed value and generate a key table including the generated random values; and an encryptor configured to apply the generated key table to a round function, generate a block encryption algorithm having a Feistel structure based on the round function, and encrypt a plaintext data block based on the generated block encryption algorithm.Type: ApplicationFiled: December 28, 2015Publication date: May 4, 2017Applicants: SAMSUNG SDS CO., LTD., CARMEL HAIFA UNIVERSITY ECONOMIC CORP. LTD., BAR-ILAN UNIVERSITYInventors: Duk-Jae MOON, Ji-Hoon CHO, Kyu-Young CHOI, Nathan KELLER, Orr DUNKELMAN, Itai DINUR
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Publication number: 20140248371Abstract: A conditioned cell culture medium of cells derived from Spalax or naked mole rat (Heterocephalus glaber) and methods for preparing it are provided. Pharmaceutical compositions comprising the conditioned cell culture medium and its use in the treatment of cancer as well as methods for identifying anti-cancer agents are also provided.Type: ApplicationFiled: January 9, 2014Publication date: September 4, 2014Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.Inventors: Aaron Avivi, Imad Shams, Irena Manov
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Publication number: 20140234826Abstract: System and method for improving reading speed and comprehension of a user that use a special software application operable through a computer processor. The method and system are configured for receiving personal details and reading level of the user; setting initial presentation pace and acceleration rate; presenting textual content over a computer screen, selected according to the received reading level and personal details; determining a current presentation pace according to the initial presentation pace and acceleration rate at each given timeframe; and manipulating presentation of text parts of the presented textual content at each given timeframe, according to the current presentation pace. The manipulation is done by erasing or blurring these text parts at a rate that corresponds to the current presentation pace.Type: ApplicationFiled: March 6, 2014Publication date: August 21, 2014Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD.Inventor: Zvia Breznitz
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Patent number: 8799289Abstract: The present invention provides an electronic documents management system and method for classifying, publishing, searching and locating electronic documents. Electronic documents are classified and published via an ontological description consisting of at least one vector, each vector comprising at least one feature-value pair. Each vector's slot corresponds to a feature and the vector's range of each slot corresponds to the set of all possible values of each feature. In order to classify an electronic document, two hashing functions are applied. A first hashing function maps each feature to a slot number, corresponding to a coordinate in the appropriate vector. A second hashing function maps the value of each pair to a numeric value of a slot, corresponding to the range of each coordinate. The result of the two hashing functions is an ordered vector that can be mapped to a node in hypercube.Type: GrantFiled: September 1, 2005Date of Patent: August 5, 2014Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Yosef Ben Asher, Shlomo Berkovsky
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Publication number: 20130236447Abstract: Inhibition of eIF-2? phosphorylation can be used to improve cognitive function and/or to treat dementia, including Alzheimer's Disease. In particular, this can be achieved by inhibiting the kinase activity of PKR in a non-toxic manner.Type: ApplicationFiled: December 17, 2012Publication date: September 12, 2013Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP., LTD.Inventors: Yaacov ROSENBLUM, Elad STERN, Yifat SEGEV
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Patent number: 8093031Abstract: The invention relates to novel heparanases, heparanase splice variants, and to polynucleotides encoding them. Particularly, the invention relates to Spalax heparanases, and to Spalax and human heparanase splice variants. Heparanase splice variants can be used, for example, to modulate the activity of heparanase in diseases disorders or conditions caused by or associated with the enzymatic activity of heparanase. For instance, a splice variant capable of down regulating the activity of heparanase can be used to treat primary tumors and/or to prevent or treat metastasis.Type: GrantFiled: September 20, 2006Date of Patent: January 10, 2012Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Nicola J. Nasser, Aaron Avivi, Israel Vlodavsky, Eviatar Nevo
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Patent number: 8044190Abstract: The present invention provides a MAP kinase homologue gene, designated EhHOG, isolated from Eurotium herbariorum, a common fungal species from the extreme hypersaline environment of the Dead Sea, capable of improving tolerance of plants and other organisms to abiotic stresses such as osmotic, heat, dehydration, freezing-thawing, oxidative and salinity stress.Type: GrantFiled: September 8, 2005Date of Patent: October 25, 2011Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Eviatar Nevo, Yan Jin, Weining Song
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Publication number: 20110257988Abstract: A medical diagnosis decision support system for assisting a health professional to diagnose a medical condition. The system is first provided with an anchor condition that can be a symptom, a sign, a laboratory test result, or an imaging test results or any combination thereof The system then guides users in a series of predetermined phases regarding abstract or concrete diagnosis groups that should be considered and appropriate data that should be collected during the clinical investigation process. The system suggests history and physical examination clinical data items, laboratory, and imaging tests that should be collected in order to differentiate among alternative diagnoses. In each phase, possible diagnoses are listed and ranked.Type: ApplicationFiled: April 14, 2010Publication date: October 20, 2011Applicants: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP. LTD., MOR RESEARCH APPLICATIONS LTD.Inventors: Yaron DENEKAMP, Mor Peleg
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Publication number: 20110052566Abstract: Inhibition of eIF-2? phosphorylation can be used to improve cognitive function and/or to treat dementia, including Alzheimer's Disease. In particular, this can be achieved by inhibiting the kinase activity of PKR in a non-toxic manner.Type: ApplicationFiled: June 30, 2010Publication date: March 3, 2011Applicant: CARMEL-HAIFA UNIVERSITY ECONOMIC CORP., LTD.Inventors: Yaacov Rosenblum, Elad Stern, Yifat Segev
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Patent number: 7738402Abstract: A method for organizing a plurality of communication devices of an ad hoc communication system into a communication network. The devices are organized into one or more communication graphs where at least one of the graphs is a rooted tree. The invention also provides an ad hoc communication system wherein the devices are organized into one or more communication graphs, where at least one of the graphs is a rooted tree. A method for routing a communication session in the system is also provided where a session is routed from the calling node to the tree root and from the tree root to the called node. In a preferred embodiment, shortcuts are sought in the session route.Type: GrantFiled: December 21, 2005Date of Patent: June 15, 2010Assignee: Carmel-Haifa University Economic Corp. Ltd.Inventors: Sharoni Feldman, Yosi Ben Asher
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Publication number: 20080098010Abstract: The present invention provides an electronic documents management system and method for classifying, publishing, searching and locating electronic documents. Electronic documents are classified and published via an ontological description consisting of at least one vector, each vector comprising at least one feature-value pair. Each vector's slot corresponds to a feature and the vector's range of each slot corresponds to the set of all possible values of each feature. In order to classify an electronic document, two hashing functions are applied. A first hashing function maps each feature to a slot number, corresponding to a coordinate in the appropriate vector. A second hashing function maps the value of each pair to a numeric value of a slot, corresponding to the range of each coordinate. The result of the two hashing functions is an ordered vector that can be mapped to a node in hypercube.Type: ApplicationFiled: September 1, 2005Publication date: April 24, 2008Applicant: Carmel-Haifa University Economic Corp. LtdInventors: Yosef Ben Asher, Shlomo Berkovsky
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Publication number: 20080019996Abstract: The invention relates to a method for treatment of chronic myelogenous leukemia (CML), Ph+ acute lymphoblastic leukemia (ALL), prostate cancer and ?-globin disorders such as sickle cell anemia and ?-thalassemia, comprising administration of a mycelium extract from at least one higher Basidiomycetes medicinal mushroom selected from the group consisting of Ganoderma adspersum, Hypsizygus ulmarium, Kuehneromyces mutabilis, Omphalotus olearius, Panus conchatus, Piptoporus betulinus, Pleurotus eryngii, and Trametes zonata.Type: ApplicationFiled: August 20, 2007Publication date: January 24, 2008Applicants: Gavish-Galilee Bio Applications Ltd., Carmel-Haifa University Economic Corp. Ltd.Inventors: Jamal MAHAJNA, Majed YASSIN, Solomon WASSER
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Publication number: 20060153099Abstract: A method for organizing a plurality of communication devices of an ad hoc communication system into a communication network. The devices are organized into one or more communication graphs where at least one of the graphs is a rooted tree. The invention also provides an ad hoc communication system wherein the devices are organized into one or more communication graphs, where at least one of the graphs is a rooted tree. A method for routing a communication session in the system is also provided where a session is routed from the calling node to the tree root and from the tree root to the called node. In a preferred embodiment, shortcuts are sought in the session route.Type: ApplicationFiled: December 21, 2005Publication date: July 13, 2006Applicant: Carmel-Haifa University Economic Corp. Ltd.Inventors: Sharoni Feldman, Yosi Asher