Abstract: Provided are ARTS mimetic compounds that act as novel antagonists for XIAP and Bcl-2. Further, the novel ARTS mimetic compounds of the presently claimed subject matter induce apoptosis and/or differentiation in premalignant and malignant cells and thereby restore their normal-like phenotype. Further provided are compositions, methods and uses of said ARTS mimetic compounds in the treatment of cancer and premalignant conditions.

Abstract: Methods for dehazing a digital image and for restoring an underwater digital image. The methods include the following steps: First, clustering pixels of a digital image into haze-lines, wherein each of the haze-lines is comprised of a sub-group of the pixels that are scattered non-locally over the digital image. Second, estimating, based on the haze-lines, a transmission map of the digital image, wherein the transmission map encodes scene depth information for each pixel of the digital image. Then, for a hazy image, calculating a dehazed digital image based on the transmission map.

Abstract: A submersible vehicle comprising: an image sensor; a first illuminator; at least one hardware processor operatively coupled with said image sensor and first illuminator, and the at least one hardware processor being configured to: acquire a first image of a scene inside a medium, when there is no object along the line-of-sight (LOS), under illumination from a first location or orientation, acquire a second image of the scene inside the medium, when there is no object along the LOS, under illumination from a second, different location or orientation, and compute attenuation coefficients, one per color channel, based on backscatter in the first and second images.

Abstract: The invention provides methods for treating a subject afflicted with a memory impairment or a cognitive dysfunction. Additional methods for improving memory and memory related functions in healthy subjects are also provided. The Methods include administration of an inhibitor of Na/K-ATPase.

Abstract: Isolated DNA of the Wtk1 gene or a functional equivalent capable of conferring resistance to stripe rust, is provided, as well as artificial vectors comprising same, proteins encoded by same and nucleic acid molecules for detecting same. Transgenic plants, as well as cells, seeds, and tissue therefrom which express the Wtk1 gene or a functional equivalent thereof are also provided.

Abstract: A method comprising: automatically providing, by a client device to a server, information regarding the identity of data components comprising a user model stored at the client device, wherein each of said data components is associated with an attribute of a user of the client device; automatically identifying, by said server, data components that are missing in said user model, based, at least in part, on a reference model stored at said server; automatically sending, by said server, to said client device, said identified missing data components; automatically updating, by said client device, said user model to include said identified missing data components; and automatically sending, by said client device, data contained in one or more of said data components in said updated user model, to enable a service provided by said server.

Abstract: Methods for treating depression in, and decreasing a dose of ketamine given to, a subject in need thereof, comprising, administering a CaMKII inhibitor are provided.

Abstract: A system comprising at least two three-dimensional (3D) cameras that are each configured to produce a digital image with a depth value for each pixel of the digital image; and a processor configured to: perform inter-camera calibration by: (i) estimating a pose of a subject, based, at least in part, on a skeleton representation of a subject captured each of by said at least two 3D cameras, wherein said skeleton representation identifies a plurality of skeletal joints of said subject, and (ii) enhancing the estimated pose based, at least in part, on a 3D point cloud of a scene containing the subject, as captured by each of said at least two 3D cameras, and perform data merging of digital images captured by said at least two 3D cameras, wherein the data merging is per each of said identifications.

Abstract: The present invention provides an antagonist of a Bcl-2 prosurvival protein containing a BH3-like domain. The antagonist of the invention comprises ARTS and any fragment or peptide that comprises a BH3-like domain. The invention further provides compositions, combined compositions and kits as well as methods for treating Bcl-2 over-expressing disorders.

Abstract: A method comprising acquiring a first image of a scene inside a medium, under illumination from a first location or orientation. The method comprises an action of acquiring a second image of the scene inside the medium, under illumination from a second, different location or orientation. The method comprises an action of computing attenuation coefficients, one per color channel, based on backscatter in the first and second images.

Abstract: Methods for dehazing a digital image and for restoring an underwater digital image. The methods include the following steps: First, clustering pixels of a digital image into haze-lines, wherein each of the haze-lines is comprised of a sub-group of the pixels that are scattered non-locally over the digital image. Second, estimating, based on the haze-lines, a transmission map of the digital image, wherein the transmission map encodes scene depth information for each pixel of the digital image. Then, for a hazy image, calculating a dehazed digital image based on the transmission map.

Abstract: Methods of treating colorectal cancer using water extracts derived from dittrichia viscosa leaves are provided.

Abstract: Provided are ARTS mimetic compounds that act as novel antagonists for XIAP and Bcl-2. Further, the novel ARTS mimetic compounds of the presently claimed subject matter induce apoptosis and/or differentiation in premalignant and malignant cells and thereby restore their normal-like phenotype. Further provided are compositions, methods and uses of said ARTS mimetic compounds in the treatment of cancer and premalignant conditions.

Abstract: Embodiments disclosed herein include methods for performing intensity-modulated radiation therapy on a subject using a plurality of pencil beams. The methods can include generating a treatment plan for intensity-modulated radiation therapy that satisfies dose constraints for each of a plurality of sub-volumes. The treatment plan can be generated using a superiorization technique that reduces total variation in dose space. Additional dose-volume constraints that permit a fraction of treatment doses to violate a prescription by up to a defined percentage of intensity can be used to assist in determining the treatment plan.

Abstract: The present invention is directed to systems and methods for fast and accurate structural representation and comparison of proteins. Specifically, the present invention provides a method for retrieval of a candidate set of near structural neighbors or structurally similar proteins of a query protein. The method is based on a representation of a protein structure as a “bag of words”—a collection of small disjoint backbone protein fragments. The representation allows quick comparison procedures of the query protein structure to a large number of known protein structures obtained for example, from a repository or database of proteins.

Abstract: Eph A receptor inhibitor peptides, and particularly Eph A4 receptor inhibitor peptides, are provided. The peptides comprise a sequence derived from the G-H loop of ephrin A4. Further, pharmaceutical compositions comprising said peptides and use thereof in treating, ameliorating or preventing diseases associated with memory formation are provided.

Abstract: A conditioned medium of CD11blow macrophages and methods for preparing it are provided. Pharmaceutical compositions comprising the CD11blow macrophages conditioned medium or a culture of CD11blow macrophages and their use in the treatment of cancer or fibrosis are also provided.

Abstract: Methods of treating colorectal cancer using water extracts derived from dittrichia viscosa leaves are provided.

Abstract: A computerized method of creating a user model, comprising: 1) Providing one or more software component collections containing software components. Each of the software components is associated with a single attribute and has: a. An attribute generation engine for calculating an attribute data. b. An attribute repository which stores the attribute data. c. An output object which outputs the attribute data to another of the plurality of software components. d. A metadata field which holds an identifier relating to the respective software component. 2) Selecting by a developer, a subset of software components. 3) Defining by the developer, a plurality of data links mapping data flow among the members of the subset. 4) Generating a user model based on the subset and the data links. 5) Outputting the user model.

Abstract: The invention relates to methods for the diagnosis and prognosis of hepatic disorder and associated pathologies as well as of a solid proliferative disorder in a mammalian subject. More specifically, the methods of the invention are based on determining the expression, methylation of ARTS as well as histone trimethylation. The invention further provides therapeutic methods for treating said disorders.