Abstract: A pharmaceutical composition, having utility as a diuretic or aldosterone antagonist, comprising spironolactone and an aqueous homogenizingly effective amount of a material selected from the group consisting of (i) sodium carboxymethylcellulose, and (ii) a mixture of methylcellulose and a dimethylpolysiloxane polymer.Also disclosed is a method of diuretic or hyperaldosteronism treatment by administration of such composition, e.g., by oral administration.
Abstract: An antibiotic composition comprising rifampin, a dimethyl polysiloxane polymer, and a cationic or non-ionic surfactant, wherein the rifampin, dimethyl polysiloxane polymer, and surfactant are present in relative amounts such that the composition is aqueously homogenizable with low foaming.Also disclosed is a method of antibiotic treatment wherein such composition is administered orally, either in a solid dosage form or in an aqueous medium.