Abstract: The present invention relates to the compounds corresponding to the formula: ##STR1## in which: X, Y and Z are selected from the following combinations:(a) Y=Z=H and X is m-CH.sub.3, m,p-Cl, m-SCH.sub.3, m,o,p-F, m,p-CN,CONH.sub.2, m-CH.sub.2 CN or p-OH,(b) Z=H and X and Y are fluorine, more particularly 2,5 and 2,4,(c) Z=H, X=m-CN and Y is p-Cl or p-F, and(d) X=Y=X=OCH.sub.3 in the m,p,m positions, and to drugs in which at least one of the said compounds is present.
Abstract: The invention relates to new compounds of formula: ##STR1## R.sub.2 =H, alkyl, halogen, cycle joined to the thiophene; n=0 or 1. .beta.-blocking properties comparable to those of propranolol and/or diuretic properties comparable to those of thiazidic substances.
Type:
Grant
Filed:
December 23, 1985
Date of Patent:
May 26, 1987
Assignee:
CARPIBEM (Centre d'activite et de recherche Pharmaceutiou et Industrielee Biologique)