Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
Type:
Grant
Filed:
December 17, 2014
Date of Patent:
January 23, 2018
Assignee:
CARRUS CAPITAL CORPORATION
Inventors:
Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Grant
Filed:
November 26, 2014
Date of Patent:
January 5, 2016
Assignee:
Carrus Capital Corporation
Inventors:
Timothy J. Krieger, Patricia J. McNicol
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Application
Filed:
November 26, 2014
Publication date:
March 26, 2015
Applicant:
Carrus Capital Corporation
Inventors:
Timothy J. KRIEGER, Patricia J. McNicol
Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
Type:
Grant
Filed:
August 26, 2002
Date of Patent:
January 13, 2015
Assignee:
Carrus Capital Corporation
Inventors:
Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Grant
Filed:
June 7, 2013
Date of Patent:
January 6, 2015
Assignee:
Carrus Capital Corporation
Inventors:
Timothy J. Krieger, Patricia J. McNicol
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Grant
Filed:
March 15, 2012
Date of Patent:
June 18, 2013
Assignee:
Carrus Capital Corporation
Inventors:
Timothy J. Krieger, Patricia J. McNicol
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Application
Filed:
March 15, 2012
Publication date:
August 9, 2012
Applicant:
Carrus Capital Corporation
Inventors:
Timothy J. Krieger, Patricia J. McNicol
Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
Type:
Grant
Filed:
June 10, 2004
Date of Patent:
March 20, 2012
Assignee:
Carrus Capital Corporation
Inventors:
Timothy J. Krieger, Patricia J. McNicol