Abstract: The present invention relates to an apparatus for treating a pathology, comprising: an ultrasonic generation device (1), a remote control unit (2) to supply electricity to the device (1), electrical connection means (31, 32) between the device (1) and the control unit (2), remarkable in that the control unit (2) is programmed to assess the quality of the acoustic coupling between the ultrasonic device (1) and a tissue to be treated.

Abstract: The present invention relates to an implantable device (1) comprising: —an ultrasonic unit (11) which includes an electric connection terminal, —a support plate (12) which includes a through-opening for the connection terminal to pass through, and —an attachment piece (13) which can cooperate with the connection terminal, the attachment piece (13) including a collar for pressing the support plate (12) against the ultrasonic unit (11) when the ultrasonic unit (11), the support plate (12) and the attachment piece (13) are joined.

Abstract: The present invention relates to an acoustic window (1) suitable for implantation at an opening in a patient's skull (4), said acoustic window (1) being intended to cooperate with an external ultrasound probe (2) for the emission of ultrasound waves through the acoustic window (1), remarkable in that the acoustic window comprises a plate (11) including a plurality of through-holes (12), the distance (P) of the through-holes (12) being less than twice the wavelength of the ultrasound waves emitted by the external ultrasound probe (2).

Abstract: An assembly for imaging and/or treating brain tissue, having at least one acoustic window which comprises a plate that is transparent to ultrasonic waves, and at least one positioning marker which facilitates positioning of a probe for generating ultrasonic waves so as to be aligned with said acoustic window.

Abstract: The present invention relates to a method for controlling a probe for the treatment of brain tissue using an assembly comprising the probe and an acoustic window (1), the probe (2) including a plurality of transducers (21) for generating ultrasound waves, the method comprising: —a phase of detection: •of the probe transducers situated above the cranium (4) of the patient, and •of the probe transducers situated above the acoustic window (1), so as to permit: •deactivation of the transducers situated above the cranium (4) of the patient, •activation of the transducers situated above the acoustic window (1).

Abstract: The present invention relates to a surgical kit for use in a craniectomy procedure, the surgical kit comprising: a medical device to be implanted in a cranial bone of a patient, the medical device (10) including several transducers for emitting ultrasound waves for treatment of brain tissue, a surgical accessory (20) intended to be positioned on the cranial bone of the patient, the surgical accessory (20) including a body whose outer perimeter defines the dimensions of an opening that is to be made in the cranial bone of the patient in order to receive the medical device, characterized in that the surgical accessory (20) comprises a plurality of holes (201) formed in the body, the position of each hole (201) on the body coinciding with the position of the axis of symmetry of a respective transducer, such that the accessory is able to be positioned optimally through the joint use of a neuronavigation system.

Abstract: An apparatus having an implantable ultrasound generating treating device to induce brain disorder treatment, suitable for implantation in or under the skull bone of a patient, includes several ultrasound generating transducers, which are connectable by a common electrical connection circuit to a generator, and wherein the ultrasound generating transducers each have one or several operating frequencies. The transducers include the group of transducers having several transducers driven by a same electrical drive signal, and connected to the generator system by a common electrical connection circuit, where the electric drive signal serves both as power signal and as a control signal for operating selectively, within said group, at least one or the other of a first transducer or sub-group of transducers, and of a second transducer or sub-group of transducers. The apparatus is also used to treat brain disorders.

Abstract: The present invention relates to a pathology treatment apparatus comprising: an ultrasound generator device (1), a remote control unit (2) for delivering electricity to the device (1) during at least an activation cycle and determining and controlling the operating parameters thereof, each activation cycle (50) being preceded by a standby cycle, means (31, 32) of electrical connection between the device (1) and the control unit (2), notable in that the control unit (2) is programmed to detect a fault with the electrical connection between the device (1) and the said control unit (2) during at least a standby cycle.

Abstract: The present invention relates to an ultrasonic probe for heating, internally, an ultrasonically absorbent target medium, the probe comprising: at least one piezoelectric transducer (21) having a front face (212) intended to be positioned facing the target medium and a back face (211) opposite the front face (212), the transducer being able to emit at least one primary wave emanating from its front face and at least one secondary wave emanating from its back face, the probe being noteworthy in that it furthermore comprises: a reflector (24) facing the back face (211) of the transducer (21), the reflector (24) being suitable for reflecting the secondary wave emitted by the transducer (21); and a cooling-fluid layer (25) between the transducer (21) and the reflector (24).

Abstract: The present invention relates to a method for transiently disrupting a region of the blood-brain barrier (BBB) of a human using ultrasounds in the presence of an ultrasound contrast agent, and uses thereof. The method comprises the application of at least one ultrasound (US) beam with a pressure level higher than 1 MPa and a resonance frequency ranging from 0.5 to 1.5 MHz.

Abstract: The present invention relates to a pathology treatment apparatus comprising: an ultrasound generator device (1), a remote control unit (2) for delivering electricity to the device (1) during at least an activation cycle and determining and controlling the operating parameters thereof, each activation cycle (50) being preceded by a standby cycle, means (31, 32) of electrical connection between the device (1) and the control unit (2), notable in that the control unit (2) is programmed to detect a fault with the electrical connection between the device (1) and the said control unit (2) during at least a standby cycle.

Abstract: The present invention relates to an apparatus for the treatment of a brain affection, which comprises at least one implantable generator (4) made of non-ferromagnetic material comprising a casing (7), an ultrasound generating treating device (11) positioned into said casing to induce brain affection treatment by emission of ultrasound waves, and means for fastening the implantable casing into the skull. The apparatus further comprises a power controller (PwC) to supply electricity to the treating device of the implantable generator and to set and control its working parameters, and connecting means (6) to connect the power controller and the treating device of the implantable generator. A method for treating a brain affection with such an apparatus is also disclosed.

Abstract: The present invention relates to an apparatus for the treatment of a brain affection, which comprises at least one implantable generator (4) made of non-ferromagnetic material comprising a casing (7), an ultrasound generating treating device (11) positioned into said casing to induce brain affection treatment by emission of ultrasound waves, and means for fastening the implantable casing into the skull. The apparatus further comprises a power controller (PwC) to supply electricity to the treating device of the implantable generator and to set and control its working parameters, and connecting means (6) to connect the power controller and the treating device of the implantable generator. A method for treating a brain affection with such an apparatus is also disclosed.