Abstract: The present invention pertains to a sustained release drug delivery system hich comprises a core of active ingredient, an enteric coating, a second coating of active ingredient and lastly a readily gastric-soluble protective coating. The sustained release dosage form of this invention is useful for pharmaceutically active ingredients that have limited aqueous solubility, especially phenytoin sodium, and other pH dependent soluble drugs.
Type:
Grant
Filed:
July 7, 1998
Date of Patent:
October 19, 1999
Assignee:
Cascade Development, Inc. a subsidiary of Cardinal Health, Inc.