Abstract: A filtration system including a crossflow filter having an interior membrane and a backpulse piston-and-cylinder assembly having a first port connected to a permeate outlet of the crossflow filter and a second port positioned at a different location than the first port. The piston-and-cylinder assembly has an interior piston movable between a first position blocking fluid flow between the first port and the second port and a second position permitting fluid flow between the first and second ports. An actuator is connected to the piston so as to move the piston from the second position to the first position. The piston defines an interior chamber within the assembly. The first port and the second port are in fluid communication with the interior chamber when the piston is in the second position. A controller is connected to the actuator for causing the movement of the piston relative to a temporal event or to a pressure differential across the interior membrane of the crossflow filter.