Patents Assigned to CASSIOPEA S.P.A.
  • ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES
    Publication number: 20260000681
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to now crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: May 20, 2025
    Publication date: January 1, 2026
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES
    Publication number: 20250387412
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: September 3, 2025
    Publication date: December 25, 2025
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 12337002
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 18, 2022
    Date of Patent: June 24, 2025
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • HIGH CONCENTRATION FORMULATION
    Publication number: 20240189324
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: December 14, 2023
    Publication date: June 13, 2024
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 11938141
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: March 26, 2024
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • High concentration formulation
    Patent number: 11883415
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: January 30, 2024
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES
    Publication number: 20230104965
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9, 11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2022
    Publication date: April 6, 2023
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES
    Publication number: 20220280531
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2021
    Publication date: September 8, 2022
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • HIGH CONCENTRATION FORMULATION
    Publication number: 20220193093
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: November 23, 2021
    Publication date: June 23, 2022
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • High concentration formulation
    Patent number: 11213531
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: January 4, 2022
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Enzymatic process for obtaining 17 ?-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 11207332
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: December 28, 2021
    Assignee: Cassiopea S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • High concentration formulation
    Patent number: 10980819
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: April 20, 2021
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 10716796
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: July 21, 2020
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • HIGH CONCENTRATION FORMULATION
    Publication number: 20200222429
    Abstract: The present disclosure provides high concentration formulations of cortexolone-I 7u-propionate suitable for treating 0 alopecia.
    Type: Application
    Filed: March 24, 2020
    Publication date: July 16, 2020
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES
    Publication number: 20200155572
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2019
    Publication date: May 21, 2020
    Applicant: Cassiopea S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • High concentration formulation
    Patent number: 10603327
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: March 31, 2020
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • HIGH CONCENTRATION FORMULATION
    Publication number: 20190374553
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: August 1, 2019
    Publication date: December 12, 2019
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • HIGH CONCENTRATION FORMULATION
    Publication number: 20190282589
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: May 1, 2019
    Publication date: September 19, 2019
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 10166245
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: January 1, 2019
    Assignee: Cassiopea S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
    Patent number: 10159682
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 25, 2018
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro