Abstract: A multi-phasic, lyophilized, fast-dissolving dosage form (FDDF) for the delivery of a pharmaceutically active ingredient is prepared by sequential dosing of a formulation containing a non-gelling matrix forming agent and a formulation containing a gelling gelatin.

Abstract: A fluid container is provided that comprises a body portion configured to at least partially surround fluid. The container also includes a cap portion connected to and above the body portion at a frangible separation site surrounding an opening between the body portion and the cap portion. The cap portion is configured to separate from the body portion at the separation site to expose the opening when a substantially downwardly directed force is applied to a part of the cap portion at a certain radial distance from a longitudinal axis through the opening. The container can include a collar configured to be disposed at least around a part of the body portion. A portion of the collar can be configured to facilitate separation of the cap portion.

Abstract: According to one aspect of invention, a locking apparatus for a device including a container that contains at least one article is provided. The locking apparatus includes a blocking element positionable with respect to at least a portion of the container, the blocking element being movable between a first position and a second position and configured to at least partially inhibit removal of articles from the container when in the second position and to permit removal of articles when in the first position. The locking apparatus also includes a lock that optionally locks the surface in the first position to inhibit movement of the blocking element into the second position.

Abstract: This invention container comprises a container shell comprising a body portion, adjoining cap portion and enclosed stopper, and an engineered separation site to facilitate separation of body and cap. The stopper has a raised nipple on the stopper, positioned such that a portion of the stopper is enclosed within the body portion and a portion of the stopper is enclosed within the cap portion. When the cap portion is removed from the body portion, a portion of the nipple therefore extends out of the body portion, allowing easy access to the stopper for cleaning or contents removal. In addition, there is an engineered separation site which includes a partial attenuation of the thickness of part of the container wall. Raised gussets are provided to enhance the cooperation between the instant invention and various needle-free connectors known in the art.