Abstract: 4-O esters of podophyllotoxin and 4?-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4?-demethylepipodophyllotoxin. The compounds are useful for treating cancer.
Type:
Grant
Filed:
July 1, 2003
Date of Patent:
March 11, 2008
Assignees:
California Pacific Medical Center, Catholic Healthcare West, DBA St. Mary's Medical Center