Abstract: The present invention relates to the use of SIRT7 (sirtuin 7) as a marker for diagnosis of liver cancer. More specifically, the invention relates to a liver cancer diagnostic marker comprising SIRT7 gene, a liver cancer diagnostic composition, kit and microarray comprising the same, and a method of diagnosing liver cancer using the same. The invention also relates to a method for screening a substance capable of preventing or treating liver cancer by inhibiting the expression of SIRT7 gene or protein, and to a composition for preventing or treating liver cancer, which comprises the substance. The expression level of SIRT7 gene is higher in liver cancer tissue or cells than in non-liver cancer tissue or cells. Thus, when SIRT7 gene is used as a cancer diagnostic marker, cancer can be early diagnosed and predicted in a rapid and accurate manner, and it can be used as a target for development of an agent for preventing or treating cancer.

Abstract: The method of face model alignment on unseen face includes inputting a face image; warping the face image into a standard shaped face based on a model seen by AAM (Active Appearance Model); normalizing the warped image by removing a texture change of the warped image; extracting a face texture from the normalized image; calculating error areas by comparing the face texture with the seen model; and aligning edges of the face texture with edges of the seen model while reducing the difference of the error areas.

Abstract: The method for extracting salient object from stereoscopic video includes: dividing regions based on the similarity of color and the distance between pixels in a left-eye image and a right-eye image which are used for an input stereoscopic image; creating a disparity map based on a disparity obtained from a pixel difference of the left-eye image and the right-eye image; calculating a contrast-based saliency by comparing the divided regions and the divided regions of the disparity map; calculating a prior-knowledge-based saliency based on a prior-knowledge for the divided regions and the divided regions of the disparity map; and extracting salient regions of the image based on the contrast-based saliency and the prior-knowledge-based saliency.

Abstract: The present invention relates to the ameliorating effects of C3G (Cyanidin-3-O-?-d-glucopyranoside) on diabetic erectile dysfunction. In particular, the present invention relates to a pharmaceutical composition and food composition for preventing or treating diabetic erectile dysfunction comprising C3G. In addition, the present invention relates to a pharmaceutical composition and food composition for preventing or treating diabetic erectile dysfunction comprising extract of mulberry containing C3G.

Abstract: The invention relates to a composition for angiogenesis inhibition comprising a peroxidasin inhibitor as an effective ingredient, and more particularly, to a method of screening angiogenesis inhibitor, which includes steps of treating a test agent, and analyzing peroxidasin gene expression or protein activity, and comparing peroxidasin gene expression or protein activity between a case treated with the test agent and a case not treated with the test agent. Accordingly, since the inhibitor of the peroxidasin expression or protein activity according to the present invention can effectively inhibit migration, proliferation and tube formation of endothelial cells, the inhibitor can be effectively used for preventing or treating a variety of diseases or conditions of the diseases derived from abnormal regulation of angiogenesis.

Abstract: The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.

Abstract: The present invention relates to the therapeutic or ameliorating effects of anthocyanin extracted from black soybean on varicocele or male infertility. In particular, the present invention relates to a method for treating or ameliorating varicocele or male infertility using anthocyanin extracted from black soybean.

Abstract: Provided is an intrauterine radiation device and system having individually inflating balloons, which constantly expand the inside of the vagina to a desired degree using the balloons in accordance with treatment planning during uterine brachytherapy, which enable the position of a radiation applicator to be accurately reproduced, and which apply a precise dose of radiation determined according to the treatment planning.

Abstract: The present invention relates to a composition for inhibiting after-cataract including a hydrophilic sulfasalazine; a high content of hyaluronic acid; and a carrier containing an aqueous solution, and a method of preparing a composition for inhibiting after-cataract including the steps of adding hyaluronic acid powder to a hydrophilized sulfasalazine; and mixing the same with a specific condition.

Abstract: A method for tracking a user's gaze point using a mobile terminal is provided. The method includes detecting the user's eye area from a camera that is mounted in the mobile terminal and selecting reference points of the eye area, detecting a pupil corresponding to an interest area that is obtained from the reference points, generating a first virtual grid of the eye area using a pickup image of a gaze point of the pupil corresponding to each corner of the display and generating a second virtual grid having the same division areas as those of the first virtual grid in the display, and mapping a position of the pupil within the second virtual grid area corresponding to a position of the pupil within the first virtual grid.

Abstract: Provided is a use of an miRNA of an Epstein-Barr virus (EBV), more specifically, EBV miR-BART4-5p, miR-BART4-3p, miR-BART1-5p, miR-BART15-3p, miR-BART5-5p, miR-BART5-3p, miR-BART16-5p, miR-BART16-3p, miR-BART17-3p, miR-BART21-3p, miR-BART18-5p, miR-BART7-5p, miR-BART9-5p, miR-BART22-5p, miR-BART20-3p, miR-BART13-5p, miR-BART13-3p, miR-BART2-3p, and mimics thereof for promoting apoptosis or inhibiting cell growth.

Abstract: Provided is an automatic detection kit for automatically detecting HLA alleles using a real-time polymerase chain reaction (PCR). The real-time PCR is performed on DNA isolated from a sample using a primer which is able to specifically bind to HLA alleles and a fluorescent probe which is able to detect amplification of the HLA alleles in real time, and the HLA allele typing is performed by analyzing a fluorescence value obtained from the real-time PCR using an HLA automatic typing.

Abstract: The present invention relates to the ameliorating effects of C3G (Cyanidin-3-O-?-d-glucopyranoside) on diabetic erectile dysfunction. In particular, the present invention relates to a pharmaceutical composition and food composition for preventing or treating diabetic erectile dysfunction comprising C3G. In addition, the present invention relates to a pharmaceutical composition and food composition for preventing or treating diabetic erectile dysfunction comprising extract of mulberry containing C3G.

Abstract: The invention relates to a stereovision optometry apparatus comprising: a 3D display unit for displaying 3D image; a reference 2D display unit for displaying reference 2D image; an eyepiece in opposite side of the 2D display unit configured to view the images; a reflective minor in opposite side of the 3D display unit configured to move toward and away from the 3D display unit; and a half minor arranged between the 3D display and the reflective mirror and disposed at a point where propagation paths of the 2D image and the 3D image intersect; wherein the 2D image penetrates through the half mirror to reach the eyepiece; wherein the 3D image penetrates the half mirror to be reflected on the reflective mirror and then the reflected image is reflected on the half mirror to reach the eyepiece.

Abstract: The invention relates to a composition for angiogenesis inhibition comprising a peroxidasin inhibitor as an effective ingredient, and more particularly, to a method of screening angiogenesis inhibitor, which includes steps of treating a test agent, and analyzing peroxidasin gene expression or protein activity, and comparing peroxidasin gene expression or protein activity between a case treated with the test agent and a case not treated with the test agent. Accordingly, since the inhibitor of the peroxidasin expression or protein activity according to the present invention can effectively inhibit migration, proliferation and tube formation of endothelial cells, the inhibitor can be effectively used for preventing or treating a variety of diseases or conditions of the diseases derived from abnormal regulation of angiogenesis.

Abstract: Provided are a composition for stimulating differentiation of MSCs into osteoblasts, which includes cryptotanshinone, and an osteogenesis stimulator including cryptotanshinone and MSCs. When the cryptotanshinone is treated to the MSCs, the differentiation into osteoblasts is stimulated, and thus osteogenesis of a patient may be stimulated by directly transplanting the differentiation-induced MSCs to the patient. Accordingly, the composition or osteogenesis stimulator may be used to treat patients having disability requiring stimulation of osteogenesis such as osteoporosis, bone fracture, bone grafting including alveolar bone grafting for implant placement, or other bone defects.

Abstract: The present invention provides a pharmaceutical composition for preventing or treating rheumatoid arthritis comprising rebamipide as an active ingredient and a pharmaceutically acceptable carrier. The pharmaceutical composition may be for oral administration, for example an oral solid dosage form of a tablet or capsule form. The pharmaceutical composition may be formulated into a unit dosage form suitable for orally administering rebamipide in a dose ranging from 0.5 to 50 mg/kg, preferably from 0.6 to 6 mg/kg.

Abstract: The present invention provides a pharmaceutical composition for preventing or treating macular degeneration, which comprises benzopyran derivatives substituted with secondary amines including imidazole or pharmaceutically acceptable salts thereof as an active ingredient. The pharmaceutical composition of the present invention may be used in the form of eye drops.

Abstract: A novel marker for diagnosis of liver cancer and use thereof are provided. To be specific, a marker for diagnosis of liver cancer using over-expression of NLK (neuro-like kinase) in liver cancer cell is provided, along with a composition for diagnosis of liver cancer, a kit, a microarray, and a method for diagnosing liver cancer using the marker. Additionally, a method for screening a substance to prevent or treat liver cancer by decreasing expression of the marker gene or protein, and a composition for preventing or treating liver cancer including such substance are provided. Accordingly, the NLK gene can be efficiently used as a target for diagnosis and treatment of liver cancer.

Abstract: An apparatus and a method for diagnosing optic neuropathic diseases including glaucoma, are provided. The apparatus for diagnosing optical neuropathic diseases measures a thickness of a retinal nerve fiber layer (RNFL) using methods such as optical coherence tomography (OCT) and scanning laser polarimetry, and includes a scanning unit which scans along an optic nerve margin in the proximity of an optic nerve head, a pattern analyzing unit which analyzes a pattern of the RNFL scanned by the scanning unit, and a disease determining unit which determines a presence of the disease based on the pattern of the RNFL analyzed by the pattern analyzing unit.