Patents Assigned to CathWorks Ltd
  • Patent number: 11937963
    Abstract: Methods and systems for manually assisted definition of vascular features are described. In some embodiments, a method provides for editing of vascular paths by enabling a user to drag an erroneously segmented region of a selected vascular path into alignment with a more correctly segmented position that is depicted as a blood vessel in a vascular image. The method may use an energy function, defined as a function of position along the segmentation of the selected blood vessel, to determine how a vascular path is to be moved based on dragging motions provided by the user. In some instances, non-zero regions of the energy function are set based on the position of the selected region.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: March 26, 2024
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Ofek Shilon, Sarit Semo, Omri Harish, Asaf Shimshovitz
  • Patent number: 11816837
    Abstract: Automated image analysis used in vascular state modeling. Coronary vasculature in particular is modeled in some embodiments. Methods of “virtual revascularization” of a presently stenotic vasculature are described; useful, for example, as a reference in disease state determinations. Structure and uses of a model which relates records comprising acquired images or other structured data to a vascular tree representation are described.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: November 14, 2023
    Assignee: Cathworks Ltd.
    Inventors: Guy Lavi, Uri Merhav, Ifat Lavi
  • Patent number: 11728037
    Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processes the images to produce a stenotic model over the vasculature. The stenotic model has measurements of the vasculature at one or more locations along vessels of the vasculature. The apparatus, in some embodiments, determines a flow characteristic of the stenotic model and calculates an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: August 15, 2023
    Assignee: CathWorks Ltd.
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 11707196
    Abstract: An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: July 25, 2023
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Uri Merhav
  • Patent number: 11666236
    Abstract: Systems and methods are described for the compositing together of model-linked vascular data from a plurality of sources, including at least one 2-D angiography image, for display in a frame of reference of the at least one angiography image. In some embodiments, a linking model comprises a data structure configured to link locations of angiographic images to corresponding elements of non-image vascular parameter data. The linking data structure is traversed to obtain a mapping to the frame of reference of one or more of the angiographic images.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: June 6, 2023
    Assignee: CathWorks Ltd.
    Inventors: Ifat Lavi, Guy Lavi
  • Patent number: 11615894
    Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives, from a medical imaging device, a medical image of a coronary vessel tree of a subject and calculates a plurality of geometric measurements associated with individual portions of a vascular segment of the coronary vessel tree. The apparatus also determines a plurality of resistances associated with the plurality of geometric measurements associated with the individual portions of the vascular segment and determines a plurality of pressure drops across the individual portions of the vascular segment based on the determined resistances and a calculated or estimated blood flow. The apparatus further calculates based on the plurality of pressure drops, a functional index indicative of a presence or an absence of a stenosis within the vascular segment.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: March 28, 2023
    Assignee: Cathworks, Ltd.
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 11406337
    Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: August 9, 2022
    Assignee: Cathworks Ltd.
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 11278208
    Abstract: An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: March 22, 2022
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Uri Merhav
  • Patent number: 11160524
    Abstract: Methods and systems for manually assisted definition of vascular features are described. In some embodiments, a method provides for editing of vascular paths by enabling a user to drag an erroneously segmented region of a selected vascular path into alignment with a more correctly segmented position that is depicted as a blood vessel in a vascular image. The method may use an energy function, defined as a function of position along the segmentation of the selected blood vessel, to determine how a vascular path is to be moved based on dragging motions provided by the user. In some instances, non-zero regions of the energy function are set based on the position of the selected region.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: November 2, 2021
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Ofek Shilon, Sarit Semo, Omri Harish, Asaf Shimshovitz
  • Patent number: 11138733
    Abstract: Automated image analysis used in vascular state modeling. Coronary vasculature in particular is modeled in some embodiments. Methods of “virtual revascularization” of a presently stenotic vasculature are described; useful, for example, as a reference in disease state determinations. Structure and uses of a model which relates records comprising acquired images or other structured data to a vascular tree representation are described.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: October 5, 2021
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Uri Merhav, Ifat Lavi
  • Patent number: 11081237
    Abstract: A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: August 3, 2021
    Assignee: CathWorks Ltd.
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 11076770
    Abstract: Systems and methods are described for the compositing together of model-linked vascular data from a plurality of sources, including at least one 2-D angiography image, for display in a frame of reference of the at least one angiography image. In some embodiments, a linking model comprises a data structure configured to link locations of angiographic images to corresponding elements of non-image vascular parameter data. The linking data structure is traversed to obtain a mapping to the frame of reference of one or more of the angiographic images.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: August 3, 2021
    Assignee: CathWorks Ltd.
    Inventors: Ifat Lavi, Guy Lavi
  • Patent number: 11017531
    Abstract: Methods of and systems for reconstructing a vascular tree shape from vascular segments imaged in a single source 2-D projection image are described. A structuring shape comprising spatial positions of reference anatomical elements is defined, such as vascular segments in the definition of a 3-D surface model corresponding to a surface defined by an anatomical structure such as a body organ (e.g., heart). The 3-D surface model is used to create a 3-D model of anatomical elements (e.g., additional vascular segments of a cardiac vasculature) imaged in a source 2-D projection image, by back-projection to the 3-D surface model. The 3-D surface model is optionally aligned by first aligning the source 2-D projection image to the structuring shape. In some embodiments, the source 2-D projection image is registered to the 3-D surface model through the structuring shape by the source image's initial use in defining the structuring shape.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: May 25, 2021
    Assignee: CathWorks Ltd
    Inventors: Omri Harish, Ofek Shilon, Guy Lavi
  • Patent number: 10803994
    Abstract: A vascular assessment apparatus is disclosed. The apparatus is configured to receive medical images of a coronary vessel tree of a subject from a medical imaging device and analyze the medical images to identify vessel segments within the coronary vessel tree. For each identified vessel segment, the apparatus is configured to determine flow rates at each identified vessel segment and calculate an index indicative of vascular function based on the determined flow rates.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: October 13, 2020
    Assignee: CathWorks Ltd
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 10631737
    Abstract: An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a stenosis determiner configured to receive a computerized model of a plurality of vascular segments of a patient, and analyze the model to determine locations of potential lesions. The example device further includes a vascular state score calculator configured to, for each potential lesion, determine a vascular state scoring tool (“VSST”) score based on at least one of a size of the potential lesion, a distance of the potential lesion from a branch point in the plurality of vascular segments, and a distance of the potential lesion to an adjacent potential lesion. The example device also includes a user interface configured to display the VSST scores for the potential lesions.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: April 28, 2020
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Uri Merhav
  • Patent number: 10595807
    Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: March 24, 2020
    Assignee: CathWorks Ltd
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 10559388
    Abstract: A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: February 11, 2020
    Assignee: CathWorks Ltd.
    Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
  • Patent number: 10470730
    Abstract: A method for vascular modeling is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels. In some embodiments, projection and/or image registration is iteratively altered to improve feature position matching. Based on 3-D vascular extents and their registration to 2-D images, additional features such as vascular width are optionally determined and added to the model.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: November 12, 2019
    Assignee: CathWorks Ltd.
    Inventors: Nessi Benishti, Ifat Lavi, Ran Kornowski, Idit Avrahami, Guy Lavi
  • Patent number: 10441235
    Abstract: Methods and systems for manually assisted definition of vascular features are described. In some embodiments, vascular centerlines identified by image analysis are divided into segments. Optionally, one or more candidate paths extending to the vascular root position along chains of segments are generated for each of a plurality of vascular endpoint. Selection of paths which correspond to anatomical paths of blood flow is optionally based on manual review. Optionally, paths are manually defined, for example, based on selection of a plurality of waypoints. Optionally, paths are edited by use of an active contour method that allows relative rough indication of corrections to be transformed into path changes that conform closely to the geometry of nearby vasculature.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: October 15, 2019
    Assignee: CathWorks Ltd.
    Inventors: Guy Lavi, Ofek Shilon, Sarit Semo, Omri Harish, Asaf Shimshovitz
  • Patent number: 10424063
    Abstract: Automated image analysis used in vascular state modeling. Coronary vasculature in particular is modeled in some embodiments. Methods of “virtual revascularization” of a presently stenotic vasculature are described; useful, for example, as a reference in disease state determinations. Structure and uses of a model which relates records comprising acquired images or other structured data to a vascular tree representation are described.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: September 24, 2019
    Assignee: CathWorks, Ltd.
    Inventors: Guy Lavi, Uri Merhav, Ifat Lavi