Abstract: A biological detection system for detecting a liquid sample containing a plurality of target biological particles includes a capturing device including a cell structure, an inlet, an outlet, a monolithic chip, and a layer of binding agent. The monolithic chip includes a substrate and a plurality of discrete nano-sized structures which are displaced from each other and each of which extends uprightly from the substrate to terminate at a top end. The layer of binding agent is formed on the top end of each of the discrete nano-sized structures for capturing the target biological particles.

Abstract: A biological particle capturing and retrieving system includes a capturing device including a substrate, an isolating layer and a driving unit, and a retrieving device including a micropipette. The isolating layer includes a top surface, multiple pores, and multiple fluidic grooves indented from the top surface, arranged in a herringbone pattern, and each having a bottom surface. The pores are formed in the bottom surfaces of the fluidic grooves, and each capture a biological particle in a liquid sample. The driving unit drives the liquid sample to flow by electrowetting through the pores. The micropipette has a carrier coated with a biological particle-binding material binding with the biological particle received in a corresponding pore.

Abstract: A biological detection system for detecting a liquid sample containing a plurality of target biological particles includes a capturing device including a cell structure, an inlet, an outlet, a monolithic chip, and a layer of binding agent. The monolithic chip includes a substrate and a plurality of discrete nano-sized structures which are displaced from each other and each of which extends uprightly from the substrate to terminate at a top end. The layer of binding agent is formed on the top end of each of the discrete nano-sized structures for capturing the target biological particles.

Abstract: A biological particle capturing and retrieving system includes a capturing device including a substrate, an isolating layer and a driving unit, and a retrieving device including a micropipette. The isolating layer includes a top surface, multiple pores, and multiple fluidic grooves indented from the top surface, arranged in a herringbone pattern, and each having a bottom surface. The pores are formed in the bottom surfaces of the fluidic grooves, and each capture a biological particle in a liquid sample. The driving unit drives the liquid sample to flow by electrowetting through the pores. The micropipette has a carrier coated with a biological particle-binding material binding with the biological particle received in a corresponding pore.