Abstract: A manifold for water dispensing units includes a manifold body having: one or more inlet paths, an outlet path, a collecting chamber delimited by a lateral wall and communicating with the inlet paths and with the outlet path. The collecting chamber is configured to receive a cartridge body for the regulation of flow. A safety group is associated to the manifold body and includes: a flange removably attached to the manifold body, a safety shutter provided with through inlet gaps and with shut-off surfaces and a control body for the movement of the safety shutter: from a first position in which the through inlet gaps communicate with the inlet paths and contrast means prevent the separation of the control body and the cartridge body from the manifold body, to a second position in which the shut-off surfaces sealingly close the inlet paths. A sliding surface allows the separation of the control body and the cartridge body from the manifold body, and vice versa.