Abstract: Imido and amido substituted acyihydroxamidic acids which reduce the levels of TNF&agr; and inhibit phosphodiesterase in a mammal. A typical embodiment is (3-(1,3-dioxoisoindolin -2-yl)-3-(3-ethoxy-4-methoxyphenyl)propandylamino)propanoate.
Type:
Application
Filed:
February 25, 2004
Publication date:
August 26, 2004
Applicant:
Celgene
Inventors:
Hon-Wah Man, George W. Muller, Shaei Y. Huang