Patents Assigned to Celgene Corporation, et al. - Justia Patents Search

Patents Assigned to Celgene Corporation, et al.

Substituted 2-(2,6-dioxopiperidin-3-yl)- phthalimides and 1-oxoisoindolines and method of reducing TNF&agr; levels

Patent number: 6395754

Abstract: Substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines reduce the levels of TNF&agr; in a mammal. A typical embodiment is 1-oxo-2-(2,6-dioxo-3-methylpiperidin-3-yl)-4,5,6,7-tetrafluoroisoindoline.

Type: Grant

Filed: February 22, 2000

Date of Patent: May 28, 2002

Assignee: Celgene Corporation, et al.

Inventors: George W. Muller, David I. Stirling, Roger Shen-Chu Chen