Patents Assigned to Cell Singaling Technology, Inc.
  • Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
    Patent number: 7935790
    Abstract: The invention discloses 95 novel phosphorylation sites identified in signal transduction proteins and pathways downstream of the T-cell receptor, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: May 3, 2011
    Assignee: Cell Singaling Technology, Inc.
    Inventors: Albrecht Moritz, Roberto Polakiewicz, John Edward Rush, Kimberly Lee