Patents Assigned to Cellay, LLC
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Publication number: 20090215643Abstract: Disclosed are chromosome-specific synthetic oligonucleotides and labeled probe compositions, as well as related methods for preparing and using such compositions. Also disclosed are kits for utilization in methods for preparing or using the labeled probes.Type: ApplicationFiled: July 25, 2008Publication date: August 27, 2009Applicant: Cellay, LLCInventors: Joan Aurich-Costa, Sean P. Bradley, Phillip T. Moen, JR.
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Publication number: 20080171329Abstract: The invention provides methods of nucleic acid analysis. Such methods entail forming a population of gel microdrops encapsulating a population of biological entities, each entity comprising a nucleic acid, whereby at least some microdrops in the population each encapsulate a single entity. The population of gel microdrops is then contacted with a probe under conditions whereby the probe specifically hybridizes to at least one complementary sequence in the nucleic acid in at least one gel microdrop. At least one gel microdrop is then analyzed or detected. The biological entities can be cells, viruses, nuclei and chromosomes.Type: ApplicationFiled: October 26, 2007Publication date: July 17, 2008Applicant: Cellay, LLC c/o One Cell Systems, Inc.Inventors: Jan Trnovsky, Patricia McGrath
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Publication number: 20080160498Abstract: The invention provides methods of nucleic acid analysis. Such methods entail forming a population of gel microdrops encapsulating a population of biological entities, each entity comprising a nucleic acid, whereby at least some microdrops in the population each encapsulate a single entity. The population of gel microdrops is then contacted with a probe under conditions whereby the probe specifically hybridizes to at least one complementary sequence in the nucleic acid in at least one gel microdrop. At least one gel microdrop is then analyzed or detected. The biological entities can be cells, viruses, nuclei and chromosomes.Type: ApplicationFiled: October 5, 2007Publication date: July 3, 2008Applicant: Cellay, LLC c/o One Cell Systems, Inc.Inventors: Jan Trnovsky, Patricia McGrath
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Publication number: 20070020617Abstract: The invention provides methods of nucleic acid analysis. Such methods entail forming a population of gel microdrops encapsulating a population of biological entities, each entity comprising a nucleic acid, whereby at least some microdrops in the population each encapsulate a single entity. The population of gel microdrops is then contacted with a probe under conditions whereby the probe specifically hybridizes to at least one complementary sequence in the nucleic acid in at least one gel microdrop. At least one gel microdrop is then analyzed or detected. The biological entities can be cells, viruses, nuclei and chromosomes.Type: ApplicationFiled: April 4, 2006Publication date: January 25, 2007Applicant: Cellay, LLC c/o One Cell Systems, Inc.Inventors: Jan Trnovsky, Patricia McGrath
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Publication number: 20030207260Abstract: The invention provides methods of nucleic acid analysis. Such methods entail forming a population of gel microdrops encapsulating a population of biological entities, each entity comprising a nucleic acid, whereby at least some microdrops in the population each encapsulate a single entity. The population of gel microdrops is then contacted with a probe under conditions whereby the probe specifically hybridizes to at least one complementary sequence in the nucleic acid in at least one gel microdrop. At least one gel microdrop is then analyzed or detected. The biological entities can be cells, viruses, nuclei and chromosomes.Type: ApplicationFiled: May 2, 2003Publication date: November 6, 2003Applicant: Cellay, LLC c/o One Cell Systems, Inc.Inventors: Jan Trnovsky, Patricia McGrath
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Patent number: 6586176Abstract: The invention provides methods of nucleic acid analysis. Such methods entail forming a population of gel microdrops encapsulating a population of biological entities, each entity comprising a nucleic acid, whereby at least some microdrops in the population each encapsulate a single entity. The population of gel microdrops is then contacted with a probe under conditions whereby the probe specifically hybridizes to at least one complementary sequence in the nucleic acid in at least one gel microdrop. At least one gel microdrop is then analyzed or detected. The biological entities can be cells, viruses, nuclei and chromosomes.Type: GrantFiled: August 6, 1999Date of Patent: July 1, 2003Assignee: Cellay, LLCInventors: Jan Trnovsky, Patricia McGrath