Abstract: A 3D scaffold (3-dimensional scaffold) is comprised of a biocompatible polymer. The 3D scaffold includes a recess that is open towards the top side of the 3D scaffold as a colonization chamber for biological cells, a canal-type vessel, which at least partially surrounds the colonization chamber, a filling opening for the canal-type vessel, and an outlet opening for the canal-type vessel. A production method for the 3D scaffold is also provided and the 3D scaffold is used for colonizing the colonization chamber with biological cells.
Abstract: A method for producing a cell culture insert with at least one membrane, in particular at least one biological membrane, may include the following steps: providing at least one insert blank with at least one opening; and forming the at least one membrane in the insert blank by means of a bio-printing method.
Type:
Grant
Filed:
May 13, 2019
Date of Patent:
December 10, 2024
Assignee:
Cellbricks GmbH
Inventors:
Lutz Kloke, Alexander Thomas, Tobias Grix, Benjamin Noichl, Anna Kreuder
Abstract: A 3D scaffold of a biocompatible polymer and colonized with biological cells is provided. The biological cells can be cultured to form a 3D cell culture construct that closely approximates a physiological architecture. A method for producing the 3D scaffold colonized with biological cells is also provided.
Type:
Grant
Filed:
November 20, 2020
Date of Patent:
May 28, 2024
Assignee:
CELLBRICKS GmbH
Inventors:
Lutz Kloke, Alexander Thomas, Tobias Lam
Abstract: A 3D scaffold (3-dimensional scaffold) is comprised of a biocompatible polymer. The 3D scaffold includes a recess that is open towards the top side of the 3D scaffold as a colonization chamber for biological cells, a canal-type vessel, which at least partially surrounds the colonization chamber, a filling opening for the canal-type vessel, and an outlet opening for the canal-type vessel. A production method for the 3D scaffold is also provided and the 3D scaffold is used for colonizing the colonization chamber with biological cells.
Abstract: A 3D scaffold of a biocompatible polymer and colonized with biological cells is provided., The biological cells can be cultured to form a 3D cell culture construct that closely approximates a physiological architecture. A method for producing the 3D scaffold colonized with biological cells is also provided.
Type:
Application
Filed:
November 20, 2020
Publication date:
May 4, 2023
Applicant:
CELLBRICKS GmbH
Inventors:
Lutz Kloke, Alexander Thomas, Tobias Lam