Abstract: The present invention relates in one aspect to the use of a matrix gel comprising chondrocytes or progenitor cells thereof in a density below that of natural cartilage as a cartilage repair implant wherein said cells exhibit increases production of extracellular matrix material.
Type:
Grant
Filed:
August 31, 2007
Date of Patent:
July 7, 2015
Assignee:
CELLCOTEC B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Jens Uwe Riesle
Abstract: The invention relates to the field of medical science, in particular to technology directed at repairing defects in living, preferably human, tissue. The present invention provides a method for inducing differentiation of multipotent cells to a desired cell type, as well as a method for repairing a tissue defect in a human or animal patient using the concept of said method for inducing differentiation of multipotent cells. The invention further relates to a kit for carrying out the method for repairing a tissue defect.
Type:
Grant
Filed:
August 29, 2011
Date of Patent:
August 5, 2014
Assignee:
CellCoTec B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Mark Ewart De Bruijn, Jens Uwe Riesle
Abstract: An automated or semi-automated module-based cartilage cell processing device (20) for preparing a cell seeded carrier (27a) from a biological material, comprising at least a cartilage preparation module (21), a cell isolation module (22), a cell mixing module (29) and a carrier cell seeding module (29a). The invention further relates to the individual modules of the module-based cartilage cell processing device (20).
Type:
Application
Filed:
March 22, 2012
Publication date:
April 17, 2014
Applicant:
CELLCOTEC B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Jens Uwe Riesle, Clayton Ellis Wilson, Mirella Ageeth Van Den Doel
Abstract: The invention relates to a method for isolating cells from a tissue sample. In preferred embodiments, chondrocytes are isolated from cartilage tissue in a shorter time than hitherto considered possible.
Type:
Grant
Filed:
August 31, 2007
Date of Patent:
April 15, 2014
Assignee:
Cellcotec B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Adetola Bamidele Adesida
Abstract: The invention relates to the field of medical science, in particular to technology directed at repairing defects in living, preferably human, tissue. The present invention provides a method for inducing differentiation of multipotent cells to a desired cell type, as well as a method for repairing a tissue defect in a human or animal patient using the concept of said method for inducing differentiation of multipotent cells. The invention further relates to a kit for carrying out the method for repairing a tissue defect.
Type:
Application
Filed:
August 29, 2011
Publication date:
March 1, 2012
Applicant:
CellCoTec B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Mark Ewart De Bruijn, Jens Uwe Riesle
Abstract: The invention relates to the field of medical science, in particular to technology directed at repairing defects in living, preferably human, tissue. The present invention provides a method for inducing differentiation of multipotent cells to a desired cell type, as well as a method for repairing a tissue defect in a human or animal patient using the concept of said method for inducing differentiation of multipotent cells. The invention further relates to a kit for carrying out the method for repairing a tissue defect.
Type:
Grant
Filed:
March 18, 2005
Date of Patent:
November 1, 2011
Assignee:
Cellcotec B.V.
Inventors:
Jeanine Anna Alphonse Hendriks, Mark Ewart De Bruijn, Jens Uwe Riesle
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