Patents Assigned to Celldex Therapeutics Limited
  • Notch
    Patent number: 7399741
    Abstract: The present invention relates to the use of therapeutic compounds in the modification of T-cell, T-cell-antigen presenting cell (APC) interactions and the interactions between pathogenic organisms and immunocompetent cells of a host. In particular it relates to the use of these compounds in the modulation of the interaction between Notch proteins and their ligands and to the use of such compounds in the therapy of conditions such as graft rejection, autoimmunity, allergy, and asthma and infectious diseases.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: July 15, 2008
    Assignee: Celldex Therapeutics Limited
    Inventors: Jonathan Robert Lamb, Margaret Jane Dallman, Gerard Francis Hoyne