Abstract: An applicator for use with an ultrasound transducer assembly is disclosed. In an embodiment, an applicator includes a nozzle body having an interior and an exterior surface; a nozzle liner having an interior and an exterior surface and being engageable with the nozzle body such that a plurality of channels are defined at least in part by the exterior surface of the nozzle liner and the interior surface of the nozzle body, each of the plurality of channels having an inlet and an outlet; a passageway defined by a space between the nozzle body and the nozzle liner, in fluid communication with the inlets of each of the plurality of channels; and an opening sized and shaped for introducing fluid to the passageway to provide fluid flow from the outlet of each of the plurality of channels essentially simultaneously. Kits and methods are also disclosed.

Abstract: An apparatus and method are provided for generating ultrasonic energy from a non-contact distance from the surface of the wound; and delivering the generated ultrasonic energy to the wound through a gaseous medium. The generated ultrasonic energy has a significantly large amplitude such that the ultrasonic energy has an intensity capable of penetrating the wound tissue to a beneficial depth to provide a therapeutic effect for decreasing the healing time for the wound.

Abstract: An apparatus and method are provided for applying a medicament to tissue, and delivering ultrasonic energy from a non-contact distance from the tissue to the medicament and to the tissue, wherein the ultrasonic energy has intensity capable of penetrating the wound tissue to a beneficial depth to provide a therapeutic effect to the tissue, and of sonicating the medicament for causing the medicament to penetrate the tissue to a beneficial depth to provide a therapeutic effect to the tissue.

Abstract: A removable applicator nozzle for use in treating a wound is provided. The removable applicator nozzle includes a nozzle, a valve and a cup. The nozzle includes a proximal portion, a distal opening and a valve interface. The proximal portion of the nozzle is engagable with a portion of a transducer of an ultrasound wound therapy device. The distal opening of the nozzle allows at least a portion of a tip of the transducer to pass therethrough. The valve is engagable with the valve interface of the nozzle and the valve selectively allows fluid to flow therethrough. The cup includes an aperture and a puncturing device. The aperture is engagable with the valve and the puncturing device is able to puncture a bottle that is inserted on the cup. Fluid flows from the bottle, through the aperture and the valve and onto a tip of the transducer. The fluid is then moved to the distal opening of the nozzle by a vacuum effect.

Abstract: A removable applicator nozzle for use in treating a wound is provided. The removable applicator nozzle includes a nozzle, a valve and a cup. The nozzle includes a proximal portion, a distal opening and a valve interface. The proximal portion of the nozzle is engagable with a portion of a transducer of an ultrasound wound therapy device. The distal opening of the nozzle allows at least a portion of a tip of the transducer to pass therethrough. The valve is engagable with the valve interface of the nozzle and the valve selectively allows fluid to flow therethrough. The cup includes an aperture and a puncturing device. The aperture is engagable with the valve and the puncturing device is able to puncture a bottle that is inserted on the cup. Fluid flows from the bottle, through the aperture and the valve and onto a tip of the transducer. The fluid is then moved to the distal opening of the nozzle by a vacuum effect.

Abstract: The present invention provides improved methods for skin grafting using ultrasonic energy.

Abstract: The invention provides methods for treating inflammatory disorders by administering low frequency ultrasound energy to decrease the inflammatory response. Exemplary inflammatory disorders are rheumatoid disorders including, but not limited to, rheumatoid arthritis, juvenile arthritis, bursitis, gout, spondylitis, scleroderma, Still's disease, and vasculitis.

Abstract: The invention provides methods for treating inflammatory skin disorders by administering low frequency ultrasound energy to decrease the inflammatory response. Exemplary skin disorders that can be treated include acne, rosacea, psoriasis, atopic dermatitis, seborrheic dermatitis, and contact dermatitis.

Abstract: The invention provides a multi-channel applicator nozzle.

Abstract: A nozzle for ultrasound wound treatment comprising a main body with proximal and distal ends, a reservoir and valve. The proximal end of the nozzle being removably attached to an ultrasound transducer. The distal end of the nozzle being marginally close and coaxial to the free distal end of the ultrasound transducer. The body of the nozzle connected with liquid reservoir, which holds the wound treatment solution and delivers same to the free end of ultrasound tip directly or through a tube. The nozzle is provided with valve for controlling flow rate of wound treatment solution. The nozzle can mix different liquids or a liquid with a gas and deliver same to the wound surface. The nozzle can also be provided with trigger system for one hand use. The present invention is a device, using ultrasonic waves to create, direct and deliver liquid treatment spray to a wound surface.

Abstract: An end-effector configured and dimensioned for being connected to an ultrasound surgical device is provided. The end-effector includes means for receiving ultrasound waves generated and propagated by the ultrasound surgical device, and means for debriding tissue on a wound surface. The means for debriding tissue includes at least one non-smooth surface; and means for propagating the received ultrasound waves to the at least one non-smooth surface for vibrating the at least one non-smooth surface, wherein the at least one non-smooth vibrating surface is configured to contact and debride tissue on the wound surface. A method is further provided for debriding wound tissue including the steps of providing ultrasound waves to a non-smooth surface configured for debriding, propagating the ultrasound waves to cause vibration of the non-smooth surface, and contacting the vibrating surface configured for debriding with the wound tissue.

Abstract: The invention provides a multi-channel applicator nozzle.

Abstract: The invention provides devices to prevent re-use of an ultrasound applicator.

Abstract: A removable applicator nozzle for use in treating a wound is provided. The removable applicator nozzle includes a nozzle, a valve and a cup. The nozzle includes a proximal portion, a distal opening and a valve interface. The proximal portion of the nozzle is engagable with a portion of a transducer of an ultrasound wound therapy device. The distal opening of the nozzle allows at least a portion of a tip of the transducer to pass therethrough. The valve is engagable with the valve interface of the nozzle and the valve selectively allows fluid to flow therethrough. The cup includes an aperture and a puncturing device. The aperture is engagable with the valve and the puncturing device is able to puncture a bottle that is inserted on the cup. Fluid flows from the bottle, through the aperture and the valve and onto a tip of the transducer. The fluid is then moved to the distal opening of the nozzle by a vacuum effect.