Abstract: The present disclosure relates to neurotoxins and uses thereof. In particular, provided herein are botulinum neurotoxins with altered properties and uses thereof (e.g., research, screening, and therapeutic uses).
Type:
Grant
Filed:
October 25, 2017
Date of Patent:
August 25, 2020
Assignee:
CELLSNAP LLC
Inventors:
Eric A. Johnson, Sabine Pellett, William H. Tepp, Christina Pier, Marite Bradshaw
Abstract: The present disclosure relates to chimeric neurotoxins and uses thereof. In particular, provided herein are chimeric botulinum neurotoxins with altered properties and uses thereof (e.g., research, screening, and therapeutic uses).
Type:
Grant
Filed:
January 10, 2018
Date of Patent:
June 23, 2020
Assignee:
CELLSNAP LLC
Inventors:
Eric A. Johnson, Sabine Pellett, William H. Tepp, Marite Bradshaw, Christina L. Pier, Joseph T. Barbieri
Abstract: The present invention relates to compositions and methods for testing agents (e.g., Clostridium botulinum neurotoxin (BoNT) detection and analysis). In particular, the present invention relates to the use of Human induced pluripotent stem (hiPS) derived cells for agent detection and analysis.
Type:
Grant
Filed:
September 28, 2012
Date of Patent:
December 22, 2015
Assignee:
CELLSNAP, LLC
Inventors:
Eric Arthur Johnson, Sabine Pellett, William Howard Tepp, Regina Clare Meyer Whitemarsh